Ubenimex induces apoptotic and autophagic cell death in rat GH3 and MMQ cells through the ROS/ERK pathway

PURPOSE: Ubenimex, an aminopeptidase N (APN) inhibitor, is widely known for its use as an adjunct therapy for cancer therapy. However, in recent studies, it has also conferred antitumour effects in many cancers, but its anticancer mechanism is largely unknown. This study aims to investigate the spec...

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Detalles Bibliográficos
Autores principales: Wang, Yanjun, Pang, Bo, Zhang, Rui, Fu, Yibing, Pang, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750015/
https://www.ncbi.nlm.nih.gov/pubmed/31571825
http://dx.doi.org/10.2147/DDDT.S218371

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750015/
https://www.ncbi.nlm.nih.gov/pubmed/31571825
http://dx.doi.org/10.2147/DDDT.S218371

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