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A Coding Sequence-Embedded Principle Governs Translational Reading Frame Fidelity
Upon initiation at a start codon, the ribosome must maintain the correct reading frame for hundreds of codons in order to produce functional proteins. While some sequence elements are able to trigger programmed ribosomal frameshifting (PRF), very little is known about how the ribosome normally preve...
Autores principales: | Wan, Ji, Gao, Xiangwei, Mao, Yuanhui, Zhang, Xingqian, Qian, Shu-Bing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AAAS
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750092/ https://www.ncbi.nlm.nih.gov/pubmed/31549036 http://dx.doi.org/10.1155/2018/7089174 |
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