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Evaluating the IgMi mouse as a novel tool to study B‐cell biology
The IgMi mouse fails to secrete antibodies or class switch its BCR from IgM. Our study reveals that other cellular compartments, including B‐cell subsets, DC subsets, GC B cells and T(FH) cells are perturbed in the IgMi mouse, thus presenting important additional considerations when using the mouse...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750126/ https://www.ncbi.nlm.nih.gov/pubmed/30315705 http://dx.doi.org/10.1002/eji.201847735 |