Cargando…

Neutrophil–lymphocyte ratio as an early predictor for patients with acute paraquat poisoning: A retrospective analysis

This retrospective study aimed to investigate whether the neutrophil–lymphocyte ratio (NLR) can be used as an early predictor of 90-day survival in patients with acute paraquat (PQ) poisoning. This study enrolled 105 patients with acute PQ poisoning admitted from May 2012 to May 2018. Kaplan–Meier c...

Descripción completa

Detalles Bibliográficos
Autores principales: Cao, Zong Xun, Song, Ya Qi, Bai, Wen Jing, Wang, Wen Jie, Zhao, Yong, Zhang, Su Li, Feng, Shun Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750259/
https://www.ncbi.nlm.nih.gov/pubmed/31517877
http://dx.doi.org/10.1097/MD.0000000000017199
_version_ 1783452428829458432
author Cao, Zong Xun
Song, Ya Qi
Bai, Wen Jing
Wang, Wen Jie
Zhao, Yong
Zhang, Su Li
Feng, Shun Yi
author_facet Cao, Zong Xun
Song, Ya Qi
Bai, Wen Jing
Wang, Wen Jie
Zhao, Yong
Zhang, Su Li
Feng, Shun Yi
author_sort Cao, Zong Xun
collection PubMed
description This retrospective study aimed to investigate whether the neutrophil–lymphocyte ratio (NLR) can be used as an early predictor of 90-day survival in patients with acute paraquat (PQ) poisoning. This study enrolled 105 patients with acute PQ poisoning admitted from May 2012 to May 2018. Kaplan–Meier curve, receiver operating characteristic curve, and Cox proportional hazards regression analyses were used to investigate the predictive value of NLR for 90–day survival of patients with acute PQ poisoning. The 90-day survival rate was 40.95% (43/105). Survivors had lower NLR (P <.001), which was an independent predictor of 90-day survival according to the Cox proportional hazard regression analyses. The area under the NLR curve was 0.842 (95% CI: 0.767–0.917, P <.001) in predicting 90-day survival. Our findings showed that low NLR was a valuable early predictor of 90-day survival in patients with acute PQ poisoning.
format Online
Article
Text
id pubmed-6750259
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Wolters Kluwer Health
record_format MEDLINE/PubMed
spelling pubmed-67502592019-10-03 Neutrophil–lymphocyte ratio as an early predictor for patients with acute paraquat poisoning: A retrospective analysis Cao, Zong Xun Song, Ya Qi Bai, Wen Jing Wang, Wen Jie Zhao, Yong Zhang, Su Li Feng, Shun Yi Medicine (Baltimore) 3900 This retrospective study aimed to investigate whether the neutrophil–lymphocyte ratio (NLR) can be used as an early predictor of 90-day survival in patients with acute paraquat (PQ) poisoning. This study enrolled 105 patients with acute PQ poisoning admitted from May 2012 to May 2018. Kaplan–Meier curve, receiver operating characteristic curve, and Cox proportional hazards regression analyses were used to investigate the predictive value of NLR for 90–day survival of patients with acute PQ poisoning. The 90-day survival rate was 40.95% (43/105). Survivors had lower NLR (P <.001), which was an independent predictor of 90-day survival according to the Cox proportional hazard regression analyses. The area under the NLR curve was 0.842 (95% CI: 0.767–0.917, P <.001) in predicting 90-day survival. Our findings showed that low NLR was a valuable early predictor of 90-day survival in patients with acute PQ poisoning. Wolters Kluwer Health 2019-09-13 /pmc/articles/PMC6750259/ /pubmed/31517877 http://dx.doi.org/10.1097/MD.0000000000017199 Text en Copyright © 2019 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc-nd/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0
spellingShingle 3900
Cao, Zong Xun
Song, Ya Qi
Bai, Wen Jing
Wang, Wen Jie
Zhao, Yong
Zhang, Su Li
Feng, Shun Yi
Neutrophil–lymphocyte ratio as an early predictor for patients with acute paraquat poisoning: A retrospective analysis
title Neutrophil–lymphocyte ratio as an early predictor for patients with acute paraquat poisoning: A retrospective analysis
title_full Neutrophil–lymphocyte ratio as an early predictor for patients with acute paraquat poisoning: A retrospective analysis
title_fullStr Neutrophil–lymphocyte ratio as an early predictor for patients with acute paraquat poisoning: A retrospective analysis
title_full_unstemmed Neutrophil–lymphocyte ratio as an early predictor for patients with acute paraquat poisoning: A retrospective analysis
title_short Neutrophil–lymphocyte ratio as an early predictor for patients with acute paraquat poisoning: A retrospective analysis
title_sort neutrophil–lymphocyte ratio as an early predictor for patients with acute paraquat poisoning: a retrospective analysis
topic 3900
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750259/
https://www.ncbi.nlm.nih.gov/pubmed/31517877
http://dx.doi.org/10.1097/MD.0000000000017199
work_keys_str_mv AT caozongxun neutrophillymphocyteratioasanearlypredictorforpatientswithacuteparaquatpoisoningaretrospectiveanalysis
AT songyaqi neutrophillymphocyteratioasanearlypredictorforpatientswithacuteparaquatpoisoningaretrospectiveanalysis
AT baiwenjing neutrophillymphocyteratioasanearlypredictorforpatientswithacuteparaquatpoisoningaretrospectiveanalysis
AT wangwenjie neutrophillymphocyteratioasanearlypredictorforpatientswithacuteparaquatpoisoningaretrospectiveanalysis
AT zhaoyong neutrophillymphocyteratioasanearlypredictorforpatientswithacuteparaquatpoisoningaretrospectiveanalysis
AT zhangsuli neutrophillymphocyteratioasanearlypredictorforpatientswithacuteparaquatpoisoningaretrospectiveanalysis
AT fengshunyi neutrophillymphocyteratioasanearlypredictorforpatientswithacuteparaquatpoisoningaretrospectiveanalysis