Lithium chloride with immunomodulatory function for regulating titanium nanoparticle-stimulated inflammatory response and accelerating osteogenesis through suppression of MAPK signaling pathway

BACKGROUND: Wear particle-induced inflammatory osteolysis and the consequent aseptic loosening constitute the leading reasons for prosthesis failure and revision surgery. Several studies have demonstrated that the macrophage polarization state and immune response play critical roles in periprostheti...

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Detalles Bibliográficos
Autores principales: Yang, Chao, Wang, Wei, Zhu, Kechao, Liu, Wei, Luo, Yao, Yuan, Xiangwei, Wang, Jiaxing, Cheng, Tao, Zhang, Xianlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750619/
https://www.ncbi.nlm.nih.gov/pubmed/31571859
http://dx.doi.org/10.2147/IJN.S210834

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