Perineal recurrence of prostate cancer post-brachytherapy

We present a rare case of perineal recurrence of prostate cancer post low dose rate brachytherapy. Increased levels of prostate-specific antigen were recorded 12 years post brachytherapy. Pelvic CT and MRI visualized a nodular lesion in the perineum, and positron emission tomography demonstrated cho...

Descripción completa

Detalles Bibliográficos
Autores principales: Cooper, Sian, Pillinger, Toby, Ahmed, Imtiaz, Wolfe, Konrad, Liyanage, Sidath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Institute of Radiology. 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750620/
https://www.ncbi.nlm.nih.gov/pubmed/31555469
http://dx.doi.org/10.1259/bjrcr.20180104
_version_ 1783452510472634368
author Cooper, Sian
Pillinger, Toby
Ahmed, Imtiaz
Wolfe, Konrad
Liyanage, Sidath
author_facet Cooper, Sian
Pillinger, Toby
Ahmed, Imtiaz
Wolfe, Konrad
Liyanage, Sidath
author_sort Cooper, Sian
collection PubMed
description We present a rare case of perineal recurrence of prostate cancer post low dose rate brachytherapy. Increased levels of prostate-specific antigen were recorded 12 years post brachytherapy. Pelvic CT and MRI visualized a nodular lesion in the perineum, and positron emission tomography demonstrated choline-avidity. Ultrasound-guided biopsy of the nodule was performed, yielding histology consistent with prostatic adenocarcinoma. Metastatic prostatic seeding to the perineum is a rare complication of brachytherapy. We discuss the putative mechanism, approach to diagnosis, and management.
format Online
Article
Text
id pubmed-6750620
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher The British Institute of Radiology.
record_format MEDLINE/PubMed
spelling pubmed-67506202019-09-25 Perineal recurrence of prostate cancer post-brachytherapy Cooper, Sian Pillinger, Toby Ahmed, Imtiaz Wolfe, Konrad Liyanage, Sidath BJR Case Rep Case Report We present a rare case of perineal recurrence of prostate cancer post low dose rate brachytherapy. Increased levels of prostate-specific antigen were recorded 12 years post brachytherapy. Pelvic CT and MRI visualized a nodular lesion in the perineum, and positron emission tomography demonstrated choline-avidity. Ultrasound-guided biopsy of the nodule was performed, yielding histology consistent with prostatic adenocarcinoma. Metastatic prostatic seeding to the perineum is a rare complication of brachytherapy. We discuss the putative mechanism, approach to diagnosis, and management. The British Institute of Radiology. 2019-04-29 /pmc/articles/PMC6750620/ /pubmed/31555469 http://dx.doi.org/10.1259/bjrcr.20180104 Text en © 2019 The Authors. Published by the British Institute of Radiology This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
spellingShingle Case Report
Cooper, Sian
Pillinger, Toby
Ahmed, Imtiaz
Wolfe, Konrad
Liyanage, Sidath
Perineal recurrence of prostate cancer post-brachytherapy
title Perineal recurrence of prostate cancer post-brachytherapy
title_full Perineal recurrence of prostate cancer post-brachytherapy
title_fullStr Perineal recurrence of prostate cancer post-brachytherapy
title_full_unstemmed Perineal recurrence of prostate cancer post-brachytherapy
title_short Perineal recurrence of prostate cancer post-brachytherapy
title_sort perineal recurrence of prostate cancer post-brachytherapy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750620/
https://www.ncbi.nlm.nih.gov/pubmed/31555469
http://dx.doi.org/10.1259/bjrcr.20180104
work_keys_str_mv AT coopersian perinealrecurrenceofprostatecancerpostbrachytherapy
AT pillingertoby perinealrecurrenceofprostatecancerpostbrachytherapy
AT ahmedimtiaz perinealrecurrenceofprostatecancerpostbrachytherapy
AT wolfekonrad perinealrecurrenceofprostatecancerpostbrachytherapy
AT liyanagesidath perinealrecurrenceofprostatecancerpostbrachytherapy

Ejemplares similares