Cargando…

Direct Measurement of Amorphous Solubility

[Image: see text] Amorphous materials exhibit distinct physicochemical properties compared to their respective crystalline counterparts. One of these properties, the increased solubility of amorphous materials, is exploited in the pharmaceutical industry as a way of increasing bioavailability of poo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Štukelj, Jernej, Svanbäck, Sami, Agopov, Mikael, Löbmann, Korbinian, Strachan, Clare J., Rades, Thomas, Yliruusi, Jouko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2019
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750642/ https://www.ncbi.nlm.nih.gov/pubmed/31050887 http://dx.doi.org/10.1021/acs.analchem.9b01378

Ejemplares similares

Image-based dissolution analysis for tracking the surface stability of amorphous powders
por: Štukelj, Jernej, et al.
Publicado: (2020)

Machine-Vision-Enabled Salt Dissolution Analysis
por: Štukelj, Jernej, et al.
Publicado: (2020)

Image-Based Investigation: Biorelevant Solubility of α and γ Indomethacin
por: Štukelj, Jernej, et al.
Publicado: (2019)

Improving Co-Amorphous Drug Formulations by the Addition of the Highly Water Soluble Amino Acid, Proline
por: Jensen, Katrine Tarp, et al.
Publicado: (2014)

Characterization of Amorphous and Co-Amorphous Simvastatin Formulations Prepared by Spray Drying
por: Craye, Goedele, et al.
Publicado: (2015)

Influence of Solvent Composition on the Performance of Spray-Dried Co-Amorphous Formulations
por: Mishra, Jaya, et al.
Publicado: (2018)

Hot Melt Coating of Amorphous Carvedilol
por: Bannow, Jacob, et al.
Publicado: (2020)

Multivariate Quantification of the Solid State Phase Composition of Co-Amorphous Naproxen-Indomethacin
por: Beyer, Andreas, et al.
Publicado: (2015)

The Influence of Pressure on the Intrinsic Dissolution Rate of Amorphous Indomethacin
por: Löbmann, Korbinian, et al.
Publicado: (2014)

Co-Amorphous Drug Formulations in Numbers: Recent Advances in Co-Amorphous Drug Formulations with Focus on Co-Formability, Molar Ratio, Preparation Methods, Physical Stability, In Vitro and In Vivo Performance, and New Formulation Strategies
por: Liu, Jingwen, et al.
Publicado: (2021)

Efflux Inhibitor Bicalutamide Increases Oral Bioavailability of the Poorly Soluble Efflux Substrate Docetaxel in Co-Amorphous Anti-Cancer Combination Therapy
por: Bohr, Adam, et al.
Publicado: (2019)

Process Optimization and Upscaling of Spray-Dried Drug-Amino acid Co-Amorphous Formulations
por: Kasten, Georgia, et al.
Publicado: (2019)

The Influence of Drug–Polymer Solubility on Laser-Induced In Situ Drug Amorphization Using Photothermal Plasmonic Nanoparticles
por: Hempel, Nele-Johanna, et al.
Publicado: (2021)

Investigation of the Formation Process of Two Piracetam Cocrystals during Grinding
por: Rehder, Sönke, et al.
Publicado: (2011)

Microwave-Induced In Situ Amorphization: A New Strategy for Tackling the Stability Issue of Amorphous Solid Dispersions
por: Qiang, Wei, et al.
Publicado: (2020)

Convection-Induced vs. Microwave Radiation-Induced in situ Drug Amorphization
por: Hempel, Nele-Johanna, et al.
Publicado: (2020)

Influence of the Polymer Glass Transition Temperature and Molecular Weight on Drug Amorphization Kinetics Using Ball Milling
por: Asgreen, Camilla, et al.
Publicado: (2020)

The Influence of Temperature and Viscosity of Polyethylene Glycol on the Rate of Microwave-Induced In Situ Amorphization of Celecoxib
por: Hempel, Nele-Johanna, et al.
Publicado: (2020)

Studying the Impact of the Temperature and Sorbed Water during Microwave-Induced In Situ Amorphization: A Case Study of Celecoxib and Polyvinylpyrrolidone
por: Hempel, Nele-Johanna, et al.
Publicado: (2021)

Stabilizing Mechanisms of β-Lactoglobulin in Amorphous Solid Dispersions of Indomethacin
por: Kabedev, Aleksei, et al.
Publicado: (2022)

Enabling formulations of aprepitant: in vitro and in vivo comparison of nanocrystalline, amorphous and deep eutectic solvent based formulations
por: Palmelund, Henrik, et al.
Publicado: (2021)

The Influence of Polymers on the Supersaturation Potential of Poor and Good Glass Formers
por: Blaabjerg, Lasse I., et al.
Publicado: (2018)

Hyperthermia-Induced In Situ Drug Amorphization by Superparamagnetic Nanoparticles in Oral Dosage Forms
por: Ansari, Shaquib Rahman, et al.
Publicado: (2022)

The Effect of the Molecular Weight of Polyvinylpyrrolidone and the Model Drug on Laser-Induced In Situ Amorphization
por: Hempel, Nele-Johanna, et al.
Publicado: (2021)

The Role of Configurational Entropy in Amorphous Systems
por: Graeser, Kirsten A., et al.
Publicado: (2010)

Time-Gated Raman Spectroscopy for Quantitative Determination of Solid-State Forms of Fluorescent Pharmaceuticals
por: Lipiäinen, Tiina, et al.
Publicado: (2018)

Effect of Moisture on Powder Flow Properties of Theophylline
por: Sandler, Niklas, et al.
Publicado: (2010)

A Comparative Study between A Protein Based Amorphous Formulation and Other Dissolution Rate Enhancing Approaches: A Case Study with Rifaximin
por: Zhuo, Xuezhi, et al.
Publicado: (2022)

Considerations on the Kinetic Processes in the Preparation of Ternary Co-Amorphous Systems by Milling
por: Wang, Yixuan, et al.
Publicado: (2023)

Impact of drug loading in mesoporous silica-amorphous formulations on the physical stability of drugs with high recrystallization tendency
por: Antonino, Rayane S.C.M.Q., et al.
Publicado: (2019)

Tailor-made solvents for pharmaceutical use? Experimental and computational approach for determining solubility in deep eutectic solvents (DES)
por: Palmelund, Henrik, et al.
Publicado: (2019)

Crystallization Kinetics of an Amorphous Pharmaceutical Compound Using Fluorescence-Lifetime-Imaging Microscopy
por: Rautaniemi, Kaisa, et al.
Publicado: (2018)

Properties of the Sodium Naproxen-Lactose-Tetrahydrate Co-Crystal upon Processing and Storage
por: Sovago, Ioana, et al.
Publicado: (2016)

Determination of Stable Co-Amorphous Drug–Drug Ratios from the Eutectic Behavior of Crystalline Physical Mixtures
por: Kissi, Eric Ofosu, et al.
Publicado: (2019)

Determining Thermal Conductivity of Small Molecule Amorphous Drugs with Modulated Differential Scanning Calorimetry and Vacuum Molding Sample Preparation
por: Karl, Maximilian, et al.
Publicado: (2019)

Solubility investigations in the amorphous calcium magnesium carbonate system
por: Purgstaller, Bettina, et al.
Publicado: (2019)

Recent Technologies for Amorphization of Poorly Water-Soluble Drugs
por: Kim, Do-Hyun, et al.
Publicado: (2021)

Atomic Pairwise Distribution Function Analysis of the Amorphous Phase Prepared by Different Manufacturing Routes
por: Boetker, Johan P., et al.
Publicado: (2012)

A Multivariate Approach for the Determination of the Optimal Mixing Ratio of the Non-Strong Interacting Co-Amorphous System Carvedilol-Tryptophan
por: Di, Rong, et al.
Publicado: (2021)

Molecular modeling of temperature dependence of solubility parameters for amorphous polymers
por: Chen, Xianping, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_1ea9fnnejcd9jncmlle70plub0