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Nonreciprocal and Conditional Cooperativity Directs the Pioneer Activity of Pluripotency Transcription Factors

Cooperative binding of transcription factors (TFs) to chromatin orchestrates gene expression programming and cell fate specification. However, the biophysical principles of TF cooperativity remain incompletely understood. Here we use single-molecule fluorescence microscopy to study the partnership b...

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Detalles Bibliográficos
Autores principales: Li, Sai, Zheng, Eric Bo, Zhao, Li, Liu, Shixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750763/
https://www.ncbi.nlm.nih.gov/pubmed/31484078
http://dx.doi.org/10.1016/j.celrep.2019.07.103