Cargando…

Histone deacetylase inhibitors reinforce the phenotypical markers of breast epithelial or mesenchymal cancer cells but inhibit their migratory properties

INTRODUCTION: Histone deacetylase inhibitors (HDIs) are a group of compounds that exhibit anticancer activity, but their significance and usefulness in breast cancer (BC) treatment are still controversial. The ability of cancer cells to invade and migrate is augmented by the acquisition of a mesench...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wawruszak, Anna, Gumbarewicz, Ewelina, Okon, Estera, Jeleniewicz, Witold, Czapinski, Jakub, Halasa, Marta, Okla, Karolina, Smok-Kalwat, Jolanta, Bocian, Artur, Rivero-Muller, Adolfo, Stepulak, Andrzej
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750858/ https://www.ncbi.nlm.nih.gov/pubmed/31571991 http://dx.doi.org/10.2147/CMAR.S210029

Ejemplares similares

Histone Deacetylase Inhibitors and Phenotypical Transformation of Cancer Cells
por: Wawruszak, Anna, et al.
Publicado: (2019)

Sensitization of MCF7 Cells with High Notch1 Activity by Cisplatin and Histone Deacetylase Inhibitors Applied Together
por: Wawruszak, Anna, et al.
Publicado: (2021)

Additive Pharmacological Interaction between Cisplatin (CDDP) and Histone Deacetylase Inhibitors (HDIs) in MDA-MB-231 Triple Negative Breast Cancer (TNBC) Cells with Altered Notch1 Activity—An Isobolographic Analysis
por: Wawruszak, Anna, et al.
Publicado: (2019)

Antagonistic Interaction between Histone Deacetylase Inhibitor: Cambinol and Cisplatin—An Isobolographic Analysis in Breast Cancer In Vitro Models
por: Hałasa, Marta, et al.
Publicado: (2021)

Histone Deacetylase Inhibitor SAHA as Potential Targeted Therapy Agent for Larynx Cancer Cells
por: Grabarska, Aneta, et al.
Publicado: (2017)

Valproic Acid and Breast Cancer: State of the Art in 2021
por: Wawruszak, Anna, et al.
Publicado: (2021)

Assessment of Interactions between Cisplatin and Two Histone Deacetylase Inhibitors in MCF7, T47D and MDA-MB-231 Human Breast Cancer Cell Lines – An Isobolographic Analysis
por: Wawruszak, Anna, et al.
Publicado: (2015)

Advances in Chemistry and Bioactivity of Magnoflorine and Magnoflorine-Containing Extracts
por: Okon, Estera, et al.
Publicado: (2020)

Assessment of Pharmacological Interactions between SIRT2 Inhibitor AGK2 and Paclitaxel in Different Molecular Subtypes of Breast Cancer Cells
por: Wawruszak, Anna, et al.
Publicado: (2022)

Antagonistic Pharmacological Interaction between Sirtuin Inhibitor Cambinol and Paclitaxel in Triple-Negative Breast Cancer Cell Lines: An Isobolographic Analysis
por: Wawruszak, Anna, et al.
Publicado: (2022)

Synergistic or Additive Pharmacological Interactions between Magnoflorine and Cisplatin in Human Cancer Cells of Different Histological Origin
por: Okon, Estera, et al.
Publicado: (2020)

Advancements in Zebrafish Models for Breast Cancer Research: Unveiling Biomarkers, Targeted Therapies, and Personalized Medicine
por: Wawruszak, Anna, et al.
Publicado: (2023)

Magnoflorine—Isolation and the Anticancer Potential against NCI-H1299 Lung, MDA-MB-468 Breast, T98G Glioma, and TE671 Rhabdomyosarcoma Cancer Cells
por: Okon, Estera, et al.
Publicado: (2020)

Vorinostat (SAHA) and Breast Cancer: An Overview
por: Wawruszak, Anna, et al.
Publicado: (2021)

Emodin-8-O-Glucoside—Isolation and the Screening of the Anticancer Potential against the Nervous System Tumors
por: Okon, Estera, et al.
Publicado: (2023)

MicroRNAs-Role in Lung Cancer
por: Guz, Małgorzata, et al.
Publicado: (2014)

Zingiber officinale Rosc. in the Treatment of Metabolic Syndrome Disorders—A Review of In Vivo Studies
por: Gumbarewicz, Ewelina, et al.
Publicado: (2022)

REPLACR-mutagenesis, a one-step method for site-directed mutagenesis by recombineering
por: Trehan, Ashutosh, et al.
Publicado: (2016)

How to Train a Cell–Cutting-Edge Molecular Tools
por: Czapiński, Jakub, et al.
Publicado: (2017)

Genetically Engineered Lung Cancer Cells for Analyzing Epithelial–Mesenchymal Transition
por: Kiełbus, Michał, et al.
Publicado: (2019)

Additive pharmacological interaction between sirtuin inhibitor cambinol and paclitaxel in MCF7 luminal and MDA-MB-231 triple-negative breast cancer cells
por: Wawruszak, Anna, et al.
Publicado: (2022)

Estrogen Receptor Signaling in Breast Cancer
por: Miziak, Paulina, et al.
Publicado: (2023)

Imperatorin as a Promising Chemotherapeutic Agent against Human Larynx Cancer and Rhabdomyosarcoma Cells
por: Grabarska, Aneta, et al.
Publicado: (2020)

Paving the Way toward Successful Multiple Myeloma Treatment: Chimeric Antigen Receptor T-Cell Therapy
por: Grywalska, Ewelina, et al.
Publicado: (2020)

Exploring the Significance of Immune Checkpoints and EBV Reactivation in Antibody Deficiencies with Near-Normal Immunoglobulin Levels or Hyperimmunoglobulinemia
por: Mertowska, Paulina, et al.
Publicado: (2023)

Deacetylation of Transcription Factors in Carcinogenesis
por: Halasa, Marta, et al.
Publicado: (2021)

Kaiso Protein Expression Correlates with Overall Survival in TNBC Patients
por: Bocian, Artur, et al.
Publicado: (2023)

H3K18Ac as a Marker of Cancer Progression and Potential Target of Anti-Cancer Therapy
por: Hałasa, Marta, et al.
Publicado: (2019)

Therapeutic Potential of 1,8-Dihydroanthraquinone Derivatives for Breast Cancer
por: Okon, Estera, et al.
Publicado: (2023)

Next-Generation Sequencing-Based Analysis of Clinical and Pathological Features of PIK3CA-Mutated Breast Cancer
por: Smok-Kalwat, Jolanta, et al.
Publicado: (2023)

Elevated miRNA Inversely Correlates with E-cadherin Gene Expression in Tissue Biopsies from Crohn Disease Patients in contrast to Ulcerative Colitis Patients
por: Guz, Małgorzata, et al.
Publicado: (2020)

The Importance of the Immune System and Molecular Cell Signaling Pathways in the Pathogenesis and Progression of Lung Cancer
por: Smok-Kalwat, Jolanta, et al.
Publicado: (2023)

Towards an evaluation of alcoholic liver cirrhosis and nonalcoholic fatty liver disease patients with hematological scales
por: Michalak, Agata, et al.
Publicado: (2020)

Anaerobic bacteria growth in the presence of cathelicidin LL-37 and selected ceragenins delivered as magnetic nanoparticles cargo
por: Durnaś, Bonita, et al.
Publicado: (2017)

CAR-T Cell Therapy—An Overview of Targets in Gastric Cancer
por: Bębnowska, Dominika, et al.
Publicado: (2020)

Could Immune Checkpoint Disorders and EBV Reactivation Be Connected in the Development of Hematological Malignancies in Immunodeficient Patients?
por: Mertowska, Paulina, et al.
Publicado: (2023)

Dexmedetomidine Increases MMP-12 and MBP Concentrations after Coronary Artery Bypass Graft Surgery with Extracorporeal Circulation Anaesthesia without Impacting Cognitive Function: A Randomised Control Trial
por: Kowalczyk, Michał, et al.
Publicado: (2022)

A Two-Year Follow-Up Cohort Study—Improved Clinical Control over CVD Risk Factors through Weight Loss in Middle-Aged and Older Adults
por: Macek, Pawel, et al.
Publicado: (2020)

Optimal cut-off values for anthropometric measures of obesity in screening for cardiometabolic disorders in adults
por: Macek, Pawel, et al.
Publicado: (2020)

Assessment of Age-Induced Changes in Body Fat Percentage and BMI Aided by Bayesian Modelling: A Cross-Sectional Cohort Study in Middle-Aged and Older Adults
por: Macek, Pawel, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_76n5anc2hp85q2630njl06409s