Cargando…

A study on the epidemiology of tinnitus in the United Kingdom

PURPOSE: Subjective tinnitus is a common symptom with potentially negative impact on quality of life. More research is required to gain a deeper understanding of the disease and its clinical presentation. To estimate the incidence of tinnitus and to describe patient-related characteristics such as l...

Descripción completa

Detalles Bibliográficos
Autores principales: Stohler, Nadja A, Reinau, Daphne, Jick, Susan S, Bodmer, Daniel, Meier, Christoph R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750864/
https://www.ncbi.nlm.nih.gov/pubmed/31572016
http://dx.doi.org/10.2147/CLEP.S213136
_version_ 1783452531555303424
author Stohler, Nadja A
Reinau, Daphne
Jick, Susan S
Bodmer, Daniel
Meier, Christoph R
author_facet Stohler, Nadja A
Reinau, Daphne
Jick, Susan S
Bodmer, Daniel
Meier, Christoph R
author_sort Stohler, Nadja A
collection PubMed
description PURPOSE: Subjective tinnitus is a common symptom with potentially negative impact on quality of life. More research is required to gain a deeper understanding of the disease and its clinical presentation. To estimate the incidence of tinnitus and to describe patient-related characteristics such as lifestyle factors and comorbidities. PATIENTS AND METHODS: Using the Clinical Practice Research Datalink, we calculated incidence rates of first-time diagnosed tinnitus in an adult population between 2000 and 2016. We stratified incidence rates by sex, age, and year of diagnosis. Additionally, we performed a 1:1 matched case-control study comparing body mass index, lifestyle factors and selected comorbidities between patients with incident tinnitus and tinnitus-free controls. RESULTS: We identified 109 783 adults with a first-time diagnosis of tinnitus between 2000 and 2016, yielding an overall age-standardized incidence rate of 25.0 new tinnitus cases per 10,000 person-years (95% CI: 24.6–25.5). There was a steady increase in tinnitus incidence throughout the study period. Approximately 80% of tinnitus cases were diagnosed at age 40 years or older. We observed the highest incidence rate in individuals aged 60–69 years (41.2 per 10,000 person-years, 95% CI: 40.7–41.7). Smokers and alcohol drinkers were at lower risk of being diagnosed with tinnitus compared with non-smokers and non-drinkers, respectively. The occurrence of tinnitus was strongly associated with a recent diagnosis of several otological and vestibular disorders as well as head and neck disorders. CONCLUSION: The present observational study found an increasing incidence of tinnitus over time, emphasizing the continuously growing health burden. The findings on patient characteristics, lifestyle factors, and selected comorbidities contribute to a better understanding of risk factors for tinnitus.
format Online
Article
Text
id pubmed-6750864
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Dove
record_format MEDLINE/PubMed
spelling pubmed-67508642019-09-30 A study on the epidemiology of tinnitus in the United Kingdom Stohler, Nadja A Reinau, Daphne Jick, Susan S Bodmer, Daniel Meier, Christoph R Clin Epidemiol Original Research PURPOSE: Subjective tinnitus is a common symptom with potentially negative impact on quality of life. More research is required to gain a deeper understanding of the disease and its clinical presentation. To estimate the incidence of tinnitus and to describe patient-related characteristics such as lifestyle factors and comorbidities. PATIENTS AND METHODS: Using the Clinical Practice Research Datalink, we calculated incidence rates of first-time diagnosed tinnitus in an adult population between 2000 and 2016. We stratified incidence rates by sex, age, and year of diagnosis. Additionally, we performed a 1:1 matched case-control study comparing body mass index, lifestyle factors and selected comorbidities between patients with incident tinnitus and tinnitus-free controls. RESULTS: We identified 109 783 adults with a first-time diagnosis of tinnitus between 2000 and 2016, yielding an overall age-standardized incidence rate of 25.0 new tinnitus cases per 10,000 person-years (95% CI: 24.6–25.5). There was a steady increase in tinnitus incidence throughout the study period. Approximately 80% of tinnitus cases were diagnosed at age 40 years or older. We observed the highest incidence rate in individuals aged 60–69 years (41.2 per 10,000 person-years, 95% CI: 40.7–41.7). Smokers and alcohol drinkers were at lower risk of being diagnosed with tinnitus compared with non-smokers and non-drinkers, respectively. The occurrence of tinnitus was strongly associated with a recent diagnosis of several otological and vestibular disorders as well as head and neck disorders. CONCLUSION: The present observational study found an increasing incidence of tinnitus over time, emphasizing the continuously growing health burden. The findings on patient characteristics, lifestyle factors, and selected comorbidities contribute to a better understanding of risk factors for tinnitus. Dove 2019-09-13 /pmc/articles/PMC6750864/ /pubmed/31572016 http://dx.doi.org/10.2147/CLEP.S213136 Text en © 2019 Stohler et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Stohler, Nadja A
Reinau, Daphne
Jick, Susan S
Bodmer, Daniel
Meier, Christoph R
A study on the epidemiology of tinnitus in the United Kingdom
title A study on the epidemiology of tinnitus in the United Kingdom
title_full A study on the epidemiology of tinnitus in the United Kingdom
title_fullStr A study on the epidemiology of tinnitus in the United Kingdom
title_full_unstemmed A study on the epidemiology of tinnitus in the United Kingdom
title_short A study on the epidemiology of tinnitus in the United Kingdom
title_sort study on the epidemiology of tinnitus in the united kingdom
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750864/
https://www.ncbi.nlm.nih.gov/pubmed/31572016
http://dx.doi.org/10.2147/CLEP.S213136
work_keys_str_mv AT stohlernadjaa astudyontheepidemiologyoftinnitusintheunitedkingdom
AT reinaudaphne astudyontheepidemiologyoftinnitusintheunitedkingdom
AT jicksusans astudyontheepidemiologyoftinnitusintheunitedkingdom
AT bodmerdaniel astudyontheepidemiologyoftinnitusintheunitedkingdom
AT meierchristophr astudyontheepidemiologyoftinnitusintheunitedkingdom
AT stohlernadjaa studyontheepidemiologyoftinnitusintheunitedkingdom
AT reinaudaphne studyontheepidemiologyoftinnitusintheunitedkingdom
AT jicksusans studyontheepidemiologyoftinnitusintheunitedkingdom
AT bodmerdaniel studyontheepidemiologyoftinnitusintheunitedkingdom
AT meierchristophr studyontheepidemiologyoftinnitusintheunitedkingdom