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Evaluation of hydroxyurea genotoxicity in patients with sickle cell disease
OBJECTIVE: To evaluate the induction of DNA damage in peripheral blood mononuclear cells of patients with sickle cell disease, SS and SC genotypes, treated with hydroxyurea. METHODS: The study subjects were divided into two groups: one group of 22 patients with sickle cell disease, SS and SC genotyp...
Autores principales: | de Oliveira, Emanuel Almeida Moreira, Boy, Kenia de Assis, Santos, Ana Paula Pinho, Machado, Carla da Silva, Velloso-Rodrigues, Cibele, Gerheim, Pâmela Souza Almeida Silva, Mendonça, Leonardo Meneghin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Instituto Israelita de Ensino e Pesquisa Albert Einstein
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750882/ https://www.ncbi.nlm.nih.gov/pubmed/31508660 http://dx.doi.org/10.31744/einstein_journal/2019AO4742 |
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