PTP1B negatively regulates nitric oxide-mediated Pseudomonas aeruginosa killing by neutrophils

Neutrophils play a critical role in host defense against Pseudomonas aeruginosa infection. Mechanisms underlying the negative regulation of neutrophil function in bacterial clearance remain incompletely defined. Here, we demonstrate that protein tyrosine phosphatase-1B (PTP1B) is a negative regulato...

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Detalles Bibliográficos
Autores principales: Yue, Lei, Yan, Min, Tremblay, Michel L., Lin, Tong-Jun, Li, Hua, Yang, Ting, Song, Xia, Xie, Tianhong, Xie, Zhongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750887/
https://www.ncbi.nlm.nih.gov/pubmed/31532798
http://dx.doi.org/10.1371/journal.pone.0222753

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