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Evolutionary Trajectories for the Functional Diversification of Anthracycline Methyltransferases
[Image: see text] Microbial natural products are an important source of chemical entities for drug discovery. Recent advances in understanding the biosynthesis of secondary metabolites has revealed how this rich chemical diversity is generated through functional differentiation of biosynthetic enzym...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750894/ https://www.ncbi.nlm.nih.gov/pubmed/30995392 http://dx.doi.org/10.1021/acschembio.9b00238 |