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Control of Type III Secretion System Effector/Chaperone Ratio Fosters Pathogen Adaptation to Host-Adherent Lifestyle

The transition from a planktonic lifestyle to a host-attached state is often critical for bacterial virulence. Upon attachment to host cells, enteropathogenic Escherichia coli (EPEC) employs a type III secretion system (T3SS) to inject into the host cells ∼20 effector proteins, including Tir. CesT,...

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Detalles Bibliográficos
Autores principales: Elbaz, Netanel, Socol, Yaakov, Katsowich, Naama, Rosenshine, Ilan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751064/
https://www.ncbi.nlm.nih.gov/pubmed/31530678
http://dx.doi.org/10.1128/mBio.02074-19