Heme and hemoglobin utilization by Mycobacterium tuberculosis

Iron is essential for growth of Mycobacterium tuberculosis (Mtb), but most iron in the human body is stored in heme within hemoglobin. Here, we demonstrate that the substrate-binding protein DppA of the inner membrane Dpp transporter is required for heme and hemoglobin utilization by Mtb. The 1.27 Å...

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Detalles Bibliográficos
Autores principales: Mitra, Avishek, Ko, Ying-Hui, Cingolani, Gino, Niederweis, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751184/
https://www.ncbi.nlm.nih.gov/pubmed/31534126
http://dx.doi.org/10.1038/s41467-019-12109-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751184/
https://www.ncbi.nlm.nih.gov/pubmed/31534126
http://dx.doi.org/10.1038/s41467-019-12109-5

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