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Heme and hemoglobin utilization by Mycobacterium tuberculosis
Iron is essential for growth of Mycobacterium tuberculosis (Mtb), but most iron in the human body is stored in heme within hemoglobin. Here, we demonstrate that the substrate-binding protein DppA of the inner membrane Dpp transporter is required for heme and hemoglobin utilization by Mtb. The 1.27 Å...
Autores principales: | Mitra, Avishek, Ko, Ying-Hui, Cingolani, Gino, Niederweis, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751184/ https://www.ncbi.nlm.nih.gov/pubmed/31534126 http://dx.doi.org/10.1038/s41467-019-12109-5 |
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