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MLL1 is required for PAX7 expression and satellite cell self-renewal in mice

PAX7 is a paired-homeobox transcription factor that specifies the myogenic identity of muscle stem cells and acts as a nodal factor by stimulating proliferation while inhibiting differentiation. We previously found that PAX7 recruits the H3K4 methyltransferases MLL1/2 to epigenetically activate targ...

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Detalles Bibliográficos
Autores principales:	Addicks, Gregory C., Brun, Caroline E., Sincennes, Marie-Claude, Saber, John, Porter, Christopher J., Francis Stewart, A., Ernst, Patricia, Rudnicki, Michael A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751293/ https://www.ncbi.nlm.nih.gov/pubmed/31534153 http://dx.doi.org/10.1038/s41467-019-12086-9

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