Plant-based vaccines for Alzheimer’s disease

Alzheimer’s disease (AD) is one of the major causes of chronic and progressive cognitive decline, with the pathological hallmarks of senile plaques and neurofibrillary tangles. Amyloid β peptide (Aβ) is the main component of senile plaques, and the pathological load of Aβ in the brain has been shown...

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Detalles Bibliográficos
Autores principales: ISHIURA, Shoichi, YOSHIDA, Taiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japan Academy 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751297/
https://www.ncbi.nlm.nih.gov/pubmed/31189781
http://dx.doi.org/10.2183/pjab.95.020
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author ISHIURA, Shoichi
YOSHIDA, Taiji
author_facet ISHIURA, Shoichi
YOSHIDA, Taiji
author_sort ISHIURA, Shoichi
collection PubMed
description Alzheimer’s disease (AD) is one of the major causes of chronic and progressive cognitive decline, with the pathological hallmarks of senile plaques and neurofibrillary tangles. Amyloid β peptide (Aβ) is the main component of senile plaques, and the pathological load of Aβ in the brain has been shown to be a marker of the severity of AD. To prevent the accumulation of plaques, novel and safer plant-based vaccine strategies have been suggested. In this review, we summarize the results of plant vaccines against Aβ.
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spelling pubmed-67512972019-09-25 Plant-based vaccines for Alzheimer’s disease ISHIURA, Shoichi YOSHIDA, Taiji Proc Jpn Acad Ser B Phys Biol Sci Review Alzheimer’s disease (AD) is one of the major causes of chronic and progressive cognitive decline, with the pathological hallmarks of senile plaques and neurofibrillary tangles. Amyloid β peptide (Aβ) is the main component of senile plaques, and the pathological load of Aβ in the brain has been shown to be a marker of the severity of AD. To prevent the accumulation of plaques, novel and safer plant-based vaccine strategies have been suggested. In this review, we summarize the results of plant vaccines against Aβ. The Japan Academy 2019-06-11 /pmc/articles/PMC6751297/ /pubmed/31189781 http://dx.doi.org/10.2183/pjab.95.020 Text en © 2019 The Japan Academy This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
ISHIURA, Shoichi
YOSHIDA, Taiji
Plant-based vaccines for Alzheimer’s disease
title Plant-based vaccines for Alzheimer’s disease
title_full Plant-based vaccines for Alzheimer’s disease
title_fullStr Plant-based vaccines for Alzheimer’s disease
title_full_unstemmed Plant-based vaccines for Alzheimer’s disease
title_short Plant-based vaccines for Alzheimer’s disease
title_sort plant-based vaccines for alzheimer’s disease
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751297/
https://www.ncbi.nlm.nih.gov/pubmed/31189781
http://dx.doi.org/10.2183/pjab.95.020
work_keys_str_mv AT ishiurashoichi plantbasedvaccinesforalzheimersdisease
AT yoshidataiji plantbasedvaccinesforalzheimersdisease

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