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Rescue of Noradrenergic System as a Novel Pharmacological Strategy in the Treatment of Chronic Pain: Focus on Microglia Activation

Different types of pain can evolve toward a chronic condition characterized by hyperalgesia and allodynia, with an abnormal response to normal or even innocuous stimuli, respectively. A key role in endogenous analgesia is recognized to descending noradrenergic pathways that originate from the locus...

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Detalles Bibliográficos
Autores principales:	Caraci, Filippo, Merlo, Sara, Drago, Filippo, Caruso, Giuseppe, Parenti, Carmela, Sortino, Maria Angela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751320/ https://www.ncbi.nlm.nih.gov/pubmed/31572196 http://dx.doi.org/10.3389/fphar.2019.01024

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