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The Oxysterol Synthesising Enzyme CH25H Contributes to the Development of Intestinal Fibrosis
Intestinal fibrosis and stenosis are common complications of Crohn’s disease [CD], frequently requiring surgery. Anti-inflammatory strategies can only partially prevent fibrosis; hence, anti-fibrotic therapies remain an unmet clinical need. Oxysterols are oxidised cholesterol derivatives with import...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751338/ https://www.ncbi.nlm.nih.gov/pubmed/31220227 http://dx.doi.org/10.1093/ecco-jcc/jjz039 |