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A Comparative Study of ARHI Imprinted Gene Detection and Fine-Needle Aspiration Cytology in the Differential Diagnosis of Benign and Malignant Thyroid Nodules

Aims: To compare fine-needle aspiration cytology (FNAC) with imprinted gene detection in the differential diagnosis of benign and malignant thyroid nodules. Methods: A total of 34 patients (35 cases of thyroid nodules) were examined using fine-needle puncture biopsy under ultrasound guidance, and th...

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Autores principales: Zou, Dazhong, Wu, Chengwei, Miao, Jixuan, Shao, Qing, Huang, Wenlong, Huang, Jianda, Wu, Guihua, Zhang, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751391/
https://www.ncbi.nlm.nih.gov/pubmed/31411490
http://dx.doi.org/10.1089/gtmb.2019.0028
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author Zou, Dazhong
Wu, Chengwei
Miao, Jixuan
Shao, Qing
Huang, Wenlong
Huang, Jianda
Wu, Guihua
Zhang, Qing
author_facet Zou, Dazhong
Wu, Chengwei
Miao, Jixuan
Shao, Qing
Huang, Wenlong
Huang, Jianda
Wu, Guihua
Zhang, Qing
author_sort Zou, Dazhong
collection PubMed
description Aims: To compare fine-needle aspiration cytology (FNAC) with imprinted gene detection in the differential diagnosis of benign and malignant thyroid nodules. Methods: A total of 34 patients (35 cases of thyroid nodules) were examined using fine-needle puncture biopsy under ultrasound guidance, and the biopsy tissues were examined by cytologic examination and imprinted gene detection. Combined with postoperative pathology and follow-up results, the diagnostic value and consistency of the two methods were analyzed and compared. Results: The detection of benign and malignant thyroid nodules by ARHI imprinted gene had a high consistency with FNAC, and ARHI imprinted gene detection had a higher detection rate, sensitivity, and accuracy. Conclusions: Imprinted gene detection has high accuracy and sensitivity in the differential diagnosis of benign and malignant thyroid nodules. It provides a scientific reference for clinical treatment and should be incorporated into diagnostic protocols for thyroid tumor.
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spelling pubmed-67513912019-09-19 A Comparative Study of ARHI Imprinted Gene Detection and Fine-Needle Aspiration Cytology in the Differential Diagnosis of Benign and Malignant Thyroid Nodules Zou, Dazhong Wu, Chengwei Miao, Jixuan Shao, Qing Huang, Wenlong Huang, Jianda Wu, Guihua Zhang, Qing Genet Test Mol Biomarkers Original Articles Aims: To compare fine-needle aspiration cytology (FNAC) with imprinted gene detection in the differential diagnosis of benign and malignant thyroid nodules. Methods: A total of 34 patients (35 cases of thyroid nodules) were examined using fine-needle puncture biopsy under ultrasound guidance, and the biopsy tissues were examined by cytologic examination and imprinted gene detection. Combined with postoperative pathology and follow-up results, the diagnostic value and consistency of the two methods were analyzed and compared. Results: The detection of benign and malignant thyroid nodules by ARHI imprinted gene had a high consistency with FNAC, and ARHI imprinted gene detection had a higher detection rate, sensitivity, and accuracy. Conclusions: Imprinted gene detection has high accuracy and sensitivity in the differential diagnosis of benign and malignant thyroid nodules. It provides a scientific reference for clinical treatment and should be incorporated into diagnostic protocols for thyroid tumor. Mary Ann Liebert, Inc., publishers 2019-09-01 2019-09-12 /pmc/articles/PMC6751391/ /pubmed/31411490 http://dx.doi.org/10.1089/gtmb.2019.0028 Text en © Dazhong Zou et al. 2019; Published by Mary Ann Liebert, Inc. This Open Access article is distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Zou, Dazhong
Wu, Chengwei
Miao, Jixuan
Shao, Qing
Huang, Wenlong
Huang, Jianda
Wu, Guihua
Zhang, Qing
A Comparative Study of ARHI Imprinted Gene Detection and Fine-Needle Aspiration Cytology in the Differential Diagnosis of Benign and Malignant Thyroid Nodules
title A Comparative Study of ARHI Imprinted Gene Detection and Fine-Needle Aspiration Cytology in the Differential Diagnosis of Benign and Malignant Thyroid Nodules
title_full A Comparative Study of ARHI Imprinted Gene Detection and Fine-Needle Aspiration Cytology in the Differential Diagnosis of Benign and Malignant Thyroid Nodules
title_fullStr A Comparative Study of ARHI Imprinted Gene Detection and Fine-Needle Aspiration Cytology in the Differential Diagnosis of Benign and Malignant Thyroid Nodules
title_full_unstemmed A Comparative Study of ARHI Imprinted Gene Detection and Fine-Needle Aspiration Cytology in the Differential Diagnosis of Benign and Malignant Thyroid Nodules
title_short A Comparative Study of ARHI Imprinted Gene Detection and Fine-Needle Aspiration Cytology in the Differential Diagnosis of Benign and Malignant Thyroid Nodules
title_sort comparative study of arhi imprinted gene detection and fine-needle aspiration cytology in the differential diagnosis of benign and malignant thyroid nodules
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751391/
https://www.ncbi.nlm.nih.gov/pubmed/31411490
http://dx.doi.org/10.1089/gtmb.2019.0028
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