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Recovirus NS1-2 Has Viroporin Activity That Induces Aberrant Cellular Calcium Signaling To Facilitate Virus Replication

Enteric viruses in the Caliciviridae family cause acute gastroenteritis in humans and animals, but the cellular processes needed for virus replication and disease remain unknown. A common strategy among enteric viruses, including rotaviruses and enteroviruses, is to encode a viral ion channel (i.e.,...

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Detalles Bibliográficos
Autores principales: Strtak, Alicia C., Perry, Jacob L., Sharp, Mark N., Chang-Graham, Alexandra L., Farkas, Tibor, Hyser, Joseph M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751491/
https://www.ncbi.nlm.nih.gov/pubmed/31533997
http://dx.doi.org/10.1128/mSphere.00506-19