Immunosuppression by monocytic myeloid-derived suppressor cells in patients with pancreatic ductal carcinoma is orchestrated by STAT3

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is a highly devastating disease with an overall 5-year survival rate of less than 8%. New evidence indicates that PDAC cells release pro-inflammatory metabolites that induce a marked alteration of normal hematopoiesis, favoring the expansion and ac...

Descripción completa

Detalles Bibliográficos
Autores principales: Trovato, Rosalinda, Fiore, Alessandra, Sartori, Sara, Canè, Stefania, Giugno, Rosalba, Cascione, Luciano, Paiella, Salvatore, Salvia, Roberto, De Sanctis, Francesco, Poffe, Ornella, Anselmi, Cristina, Hofer, Francesca, Sartoris, Silvia, Piro, Geny, Carbone, Carmine, Corbo, Vincenzo, Lawlor, Rita, Solito, Samantha, Pinton, Laura, Mandruzzato, Susanna, Bassi, Claudio, Scarpa, Aldo, Bronte, Vincenzo, Ugel, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751612/
https://www.ncbi.nlm.nih.gov/pubmed/31533831
http://dx.doi.org/10.1186/s40425-019-0734-6

Ejemplares similares

Ejemplares similares