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Cancer-associated fibroblast-derived Gremlin 1 promotes breast cancer progression

BACKGROUND: Bone morphogenetic proteins (BMPs) have been reported to maintain epithelial integrity and to antagonize the transforming growth factor β (TGFβ)-induced epithelial to mesenchymal transition. The expression of soluble BMP antagonists is dysregulated in cancers and interrupts proper BMP si...

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Detalles Bibliográficos
Autores principales:	Ren, Jiang, Smid, Marcel, Iaria, Josephine, Salvatori, Daniela C. F., van Dam, Hans, Zhu, Hong Jian, Martens, John W. M., ten Dijke, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751614/ https://www.ncbi.nlm.nih.gov/pubmed/31533776 http://dx.doi.org/10.1186/s13058-019-1194-0

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