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Calcineurin Broadly Regulates the Initiation of Skeletal Muscle-Specific Gene Expression by Binding Target Promoters and Facilitating the Interaction of the SWI/SNF Chromatin Remodeling Enzyme
Calcineurin (Cn) is a calcium-activated serine/threonine protein phosphatase that is broadly implicated in diverse cellular processes, including the regulation of gene expression. During skeletal muscle differentiation, Cn activates the nuclear factor of activated T-cell (NFAT) transcription factor...
Autores principales: | Witwicka, Hanna, Nogami, Jumpei, Syed, Sabriya A., Maehara, Kazumitsu, Padilla-Benavides, Teresita, Ohkawa, Yasuyuki, Imbalzano, Anthony N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751634/ https://www.ncbi.nlm.nih.gov/pubmed/31308130 http://dx.doi.org/10.1128/MCB.00063-19 |
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