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Natural selection and genetic diversity of domain I of Plasmodium falciparum apical membrane antigen-1 on Bioko Island

BACKGROUND: Plasmodium falciparum apical membrane antigen-1 (PfAMA-1) is a promising candidate antigen for a blood-stage malaria vaccine. However, antigenic variation and diversity of PfAMA-1 are still major problems to design a universal malaria vaccine based on this antigen, especially against dom...

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Detalles Bibliográficos
Autores principales: Wang, Ya-Nan, Lin, Min, Liang, Xue-Yan, Chen, Jiang-Tao, Xie, Dong-De, Wang, Yu-Ling, Ehapo, Carlos Salas, Eyi, Urbano Monsuy, Huang, Hui-Ying, Wu, Jing-Li, Xu, Dan-Yan, Chen, Zhi-Mao, Cao, Yi-Long, Chen, Hai-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751645/
https://www.ncbi.nlm.nih.gov/pubmed/31533747
http://dx.doi.org/10.1186/s12936-019-2948-y