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Natural selection and genetic diversity of domain I of Plasmodium falciparum apical membrane antigen-1 on Bioko Island

BACKGROUND: Plasmodium falciparum apical membrane antigen-1 (PfAMA-1) is a promising candidate antigen for a blood-stage malaria vaccine. However, antigenic variation and diversity of PfAMA-1 are still major problems to design a universal malaria vaccine based on this antigen, especially against dom...

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Detalles Bibliográficos
Autores principales:	Wang, Ya-Nan, Lin, Min, Liang, Xue-Yan, Chen, Jiang-Tao, Xie, Dong-De, Wang, Yu-Ling, Ehapo, Carlos Salas, Eyi, Urbano Monsuy, Huang, Hui-Ying, Wu, Jing-Li, Xu, Dan-Yan, Chen, Zhi-Mao, Cao, Yi-Long, Chen, Hai-Bin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751645/ https://www.ncbi.nlm.nih.gov/pubmed/31533747 http://dx.doi.org/10.1186/s12936-019-2948-y

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