Discovery of Inhibitors for Proliferating Cell Nuclear Antigen Using a Computational-Based Linked-Multiple-Fragment Screen

[Image: see text] Proliferating cell nuclear antigen (PCNA) is a central factor in DNA replication and repair pathways that plays an essential role in genome stability. The functional roles of PCNA are mediated through an extensive list of protein–protein interactions, each of which transmits specif...

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Detalles Bibliográficos
Autores principales: Bartolowits, Matthew D., Gast, Jonathon M., Hasler, Ashlee J., Cirrincione, Anthony M., O’Connor, Rachel J., Mahmoud, Amr H., Lill, Markus A., Davisson, Vincent Jo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751697/
https://www.ncbi.nlm.nih.gov/pubmed/31552364
http://dx.doi.org/10.1021/acsomega.9b02079

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