Cargando…
Development of a novel radioligand for imaging 18-kD translocator protein (TSPO) in a rat model of Parkinson’s disease
PURPOSE: The inflammation reaction in the brain may stimulate damage repair or possibly lead to secondary brain injury. It is often associated with activated microglia, which would overexpress 18-kDa translocator protein (TSPO). In this study, we successfully developed a new TSPO radioligand, [(18)F...
Autores principales: | Wu, Chun-Yi, Chen, Yang-Yi, Lin, Jia-Jia, Li, Jui-Ping, Chen, Jen-Kun, Hsieh, Te-Chun, Kao, Chia-Hung |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751751/ https://www.ncbi.nlm.nih.gov/pubmed/31533645 http://dx.doi.org/10.1186/s12880-019-0375-8 |
Ejemplares similares
-
(18)F-Radiolabeled Translocator Protein (TSPO) PET Tracers: Recent Development of TSPO Radioligands and Their Application to PET Study
por: Luu, Truong Giang, et al.
Publicado: (2022) -
An 18-kDa Translocator Protein (TSPO) polymorphism explains differences in binding affinity of the PET radioligand PBR28
por: Owen, David R, et al.
Publicado: (2012) -
In vivo evaluation of a novel (18)F-labeled PET radioligand for translocator protein 18 kDa (TSPO) in monkey brain
por: Yan, Xuefeng, et al.
Publicado: (2023) -
PET radioligand binding to translocator protein (TSPO) is increased in unmedicated depressed subjects
por: Richards, Erica M., et al.
Publicado: (2018) -
In response to: Anatomy of (18)F-GE180, a failed radioligand for the TSPO protein
por: Albert, Nathalie L., et al.
Publicado: (2020)