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Development of a novel radioligand for imaging 18-kD translocator protein (TSPO) in a rat model of Parkinson’s disease

PURPOSE: The inflammation reaction in the brain may stimulate damage repair or possibly lead to secondary brain injury. It is often associated with activated microglia, which would overexpress 18-kDa translocator protein (TSPO). In this study, we successfully developed a new TSPO radioligand, [(18)F...

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Detalles Bibliográficos
Autores principales: Wu, Chun-Yi, Chen, Yang-Yi, Lin, Jia-Jia, Li, Jui-Ping, Chen, Jen-Kun, Hsieh, Te-Chun, Kao, Chia-Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751751/
https://www.ncbi.nlm.nih.gov/pubmed/31533645
http://dx.doi.org/10.1186/s12880-019-0375-8

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