Organoruthenated Nitroxoline Derivatives Impair Tumor Cell Invasion through Inhibition of Cathepsin B Activity

[Image: see text] Lysosomal cysteine peptidase cathepsin B (catB) is an important tumor-promoting factor involved in tumor progression and metastasis representing a relevant target for the development of new antitumor agents. In the present study, we synthesized 11 ruthenium compounds bearing either...

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Detalles Bibliográficos
Autores principales: Mitrović, Ana, Kljun, Jakob, Sosič, Izidor, Uršič, Matija, Meden, Anton, Gobec, Stanislav, Kos, Janko, Turel, Iztok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751773/
https://www.ncbi.nlm.nih.gov/pubmed/31464130
http://dx.doi.org/10.1021/acs.inorgchem.9b01882

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751773/
https://www.ncbi.nlm.nih.gov/pubmed/31464130
http://dx.doi.org/10.1021/acs.inorgchem.9b01882

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