Catalpol Attenuates IL-1β Induced Matrix Catabolism, Apoptosis and Inflammation in Rat Chondrocytes and Inhibits Cartilage Degeneration

BACKGROUND: Chondrocyte dysfunction and apoptosis are 2 major features during the progression of osteoarthritis. Catalpol, an iridoid glycoside isolated from the root of Rehmannia, is a valuable medication with anti-inflammatory, anti-oxidative, and anti-apoptotic effects in various diseases. Howeve...

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Detalles Bibliográficos
Autores principales: Zeng, Yun-fu, Wang, Rong, Bian, Yang, Chen, Wen-sheng, Peng, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Animal Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6752111/
https://www.ncbi.nlm.nih.gov/pubmed/31484919
http://dx.doi.org/10.12659/MSM.916209

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6752111/
https://www.ncbi.nlm.nih.gov/pubmed/31484919
http://dx.doi.org/10.12659/MSM.916209

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