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Lewy body constipation
We systematically reviewed literature regarding “Lewy body constipation”, i.e., constipation due to Lewy body diseases (LBD), with minimal neurologic symptoms. Epidemiology and pathology studies showed that LBD can start with constipation alone, mostly due to neuronal loss and appearance of Lewy bod...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Japan Society of Coloproctology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6752132/ https://www.ncbi.nlm.nih.gov/pubmed/31559362 http://dx.doi.org/10.23922/jarc.2018-022 |
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author | Sakakibara, Ryuji Doi, Hirokazu Fukudo, Shin |
author_facet | Sakakibara, Ryuji Doi, Hirokazu Fukudo, Shin |
author_sort | Sakakibara, Ryuji |
collection | PubMed |
description | We systematically reviewed literature regarding “Lewy body constipation”, i.e., constipation due to Lewy body diseases (LBD), with minimal neurologic symptoms. Epidemiology and pathology studies showed that LBD can start with constipation alone, mostly due to neuronal loss and appearance of Lewy bodies in the myenteric plexus. Because LBD significantly increases with age, “Lewy body constipation” may also increase with age. Neuroimaging methods such as metaiodobenzylguanidine (MIBG) scintigraphy and dopamine transporter (DAT) scan provide a way to detect “Lewy body constipation.” Key for “Lewy body constipation” includes minimal non-motor features such as REM sleep behavior disorder (night talking). Add-on therapy may be required to ameliorate constipation in patients. Diagnosis is not always easy; therefore, collaboration of gastroenterologists and neurologists is highly recommended to maximize patients' quality of life. In conclusion, “Lewy body constipation” might become a distinct category among geriatric constipation, regarding patients' follow-up and their management. |
format | Online Article Text |
id | pubmed-6752132 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | The Japan Society of Coloproctology |
record_format | MEDLINE/PubMed |
spelling | pubmed-67521322019-09-26 Lewy body constipation Sakakibara, Ryuji Doi, Hirokazu Fukudo, Shin J Anus Rectum Colon Review Article We systematically reviewed literature regarding “Lewy body constipation”, i.e., constipation due to Lewy body diseases (LBD), with minimal neurologic symptoms. Epidemiology and pathology studies showed that LBD can start with constipation alone, mostly due to neuronal loss and appearance of Lewy bodies in the myenteric plexus. Because LBD significantly increases with age, “Lewy body constipation” may also increase with age. Neuroimaging methods such as metaiodobenzylguanidine (MIBG) scintigraphy and dopamine transporter (DAT) scan provide a way to detect “Lewy body constipation.” Key for “Lewy body constipation” includes minimal non-motor features such as REM sleep behavior disorder (night talking). Add-on therapy may be required to ameliorate constipation in patients. Diagnosis is not always easy; therefore, collaboration of gastroenterologists and neurologists is highly recommended to maximize patients' quality of life. In conclusion, “Lewy body constipation” might become a distinct category among geriatric constipation, regarding patients' follow-up and their management. The Japan Society of Coloproctology 2019-01-29 /pmc/articles/PMC6752132/ /pubmed/31559362 http://dx.doi.org/10.23922/jarc.2018-022 Text en Copyright © 2019 by The Japan Society of Coloproctology https://creativecommons.org/licenses/by-nc-nd/4.0/ Journal of the Anus, Rectum and Colon is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Review Article Sakakibara, Ryuji Doi, Hirokazu Fukudo, Shin Lewy body constipation |
title | Lewy body constipation |
title_full | Lewy body constipation |
title_fullStr | Lewy body constipation |
title_full_unstemmed | Lewy body constipation |
title_short | Lewy body constipation |
title_sort | lewy body constipation |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6752132/ https://www.ncbi.nlm.nih.gov/pubmed/31559362 http://dx.doi.org/10.23922/jarc.2018-022 |
work_keys_str_mv | AT sakakibararyuji lewybodyconstipation AT doihirokazu lewybodyconstipation AT fukudoshin lewybodyconstipation |