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Recent insights into the genotype–phenotype relationship from massively parallel genetic assays

With the molecular revolution in Biology, a mechanistic understanding of the genotype–phenotype relationship became possible. Recently, advances in DNA synthesis and sequencing have enabled the development of deep mutational scanning assays, capable of scoring comprehensive libraries of genotypes fo...

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Detalles Bibliográficos
Autores principales: Kemble, Harry, Nghe, Philippe, Tenaillon, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6752143/
https://www.ncbi.nlm.nih.gov/pubmed/31548853
http://dx.doi.org/10.1111/eva.12846

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