Suppressing Hedgehog signaling reverses drug resistance of refractory acute myeloid leukemia

BACKGROUND: Hedgehog (Hh) signaling is involved in the pathogenesis of tumors. By performing gene chip analysis, we predicted that Hh signaling might regulate multiple downstream pathways in acute myeloid leukemia (AML). METHODS: In this study, the potential role of the Hh pathway in refractory AML,...

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Detalles Bibliográficos
Autores principales: Huang, Kaikai, Sun, Zhiqiang, Ding, Bingjie, Jiang, Xuejie, Wang, Zhixiang, Zhu, Yufeng, Meng, Fanyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6752208/
https://www.ncbi.nlm.nih.gov/pubmed/31686853
http://dx.doi.org/10.2147/OTT.S216628

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