Cargando…
Translating genotype data of 44,000 biobank participants into clinical pharmacogenetic recommendations: challenges and solutions
PURPOSE: Biomedical databases combining electronic medical records and phenotypic and genomic data constitute a powerful resource for the personalization of treatment. To leverage the wealth of information provided, algorithms are required that systematically translate the contained information into...
Autores principales: | Reisberg, Sulev, Krebs, Kristi, Lepamets, Maarja, Kals, Mart, Mägi, Reedik, Metsalu, Kristjan, Lauschke, Volker M., Vilo, Jaak, Milani, Lili |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6752278/ https://www.ncbi.nlm.nih.gov/pubmed/30327539 http://dx.doi.org/10.1038/s41436-018-0337-5 |
Ejemplares similares
-
Genetic variation in the Estonian population: pharmacogenomics study of adverse drug effects using electronic health records
por: Tasa, Tõnis, et al.
Publicado: (2018) -
An exploratory phenome wide association study linking asthma and liver disease genetic variants to electronic health records from the Estonian Biobank
por: James, Glen, et al.
Publicado: (2019) -
Comparing distributions of polygenic risk scores of type 2 diabetes and coronary heart disease within different populations
por: Reisberg, Sulev, et al.
Publicado: (2017) -
Sodium content of processed foods in the United Kingdom: analysis of 44,000 foods purchased by 21,000 households(1)(2)(3)
por: Ni Mhurchu, Cliona, et al.
Publicado: (2011) -
Omics-informed CNV calls reduce false-positive rates and improve power for CNV-trait associations
por: Lepamets, Maarja, et al.
Publicado: (2022)