Cargando…

KIAA1199, a Target of MicoRNA-486-5p, Promotes Papillary Thyroid Cancer Invasion by Influencing Epithelial-Mesenchymal Transition (EMT)

BACKGROUND: KIAA1199 has been reported to be associated with malignant progression and poor clinical outcomes in various human malignancies. However, its clinical role and molecular function remain unknown in papillary thyroid cancer (PTC). MATERIAL/METHODS: The Cancer Genome Atlas (TCGA) was used t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jiao, Xuehua, Ye, Jiandong, Wang, Xiujie, Yin, Xueyan, Zhang, Guodong, Cheng, Xingbo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2019
Materias:	Lab/In Vitro Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6752488/ https://www.ncbi.nlm.nih.gov/pubmed/31501407 http://dx.doi.org/10.12659/MSM.918682

Ejemplares similares

The Expression Levels of Plasma micoRNAs in Atrial Fibrillation Patients
por: Liu, Zheng, et al.
Publicado: (2012)

Retraction: Functional analyses of micoRNA-326 in breast cancer development
Publicado: (2021)

Downregulation of KIAA1199 by miR‐486‐5p suppresses tumorigenesis in lung cancer
por: Wang, Anqi, et al.
Publicado: (2020)

Prognostic Implications of MicoRNA miR-195 Expression in Human Tongue Squamous Cell Carcinoma
por: Jia, Ling-fei, et al.
Publicado: (2013)

Identification of rat lung-specific microRNAs by micoRNA microarray: valuable discoveries for the facilitation of lung research
por: Wang, Yang, et al.
Publicado: (2007)

REGγ Is Associated with Lymph Node Metastasis and T-Stage in Papillary Thyroid Carcinoma
por: Qi, Long, et al.
Publicado: (2018)

Potential Use of 1-25-dihydroxyvitamin D in the Diagnosis and Treatment of Papillary Thyroid Cancer
por: Zhang, Ting, et al.
Publicado: (2018)

Role of Lin28A/let-7a/c-Myc Pathway in Growth and Malignant Behavior of Papillary Thyroid Carcinoma
por: Huang, Jiaqi, et al.
Publicado: (2018)

Upregulated hsa_circ_0004458 Contributes to Progression of Papillary Thyroid Carcinoma by Inhibition of miR-885-5p and Activation of RAC1
por: Jin, Xiaoyan, et al.
Publicado: (2018)

Micro-RNA-451 Reduces Proliferation of B-CPAP Human Papillary Thyroid Cancer Cells by Downregulating Expression of Activating Transcription Factor 2
por: Zhang, Mei-Feng, et al.
Publicado: (2021)

CircKIAA0907 Retards Cell Growth, Cell Cycle, and Autophagy of Gastric Cancer In Vitro and Inhibits Tumorigenesis In Vivo via the miR-452-5p/KAT6B Axis
por: Zhu, Lingyu, et al.
Publicado: (2020)

BRAF(V600E) and RET/PTC Promote Proliferation and Migration of Papillary Thyroid Carcinoma Cells In Vitro by Regulating Nuclear Factor-κB
por: Zhou, Dehua, et al.
Publicado: (2017)

Identification of KIAA1199 as a Biomarker for Pancreatic Intraepithelial Neoplasia
por: Suh, Han Na, et al.
Publicado: (2016)

Knockdown of KIAA1199 attenuates growth and metastasis of hepatocellular carcinoma
por: Liu, Jingmei, et al.
Publicado: (2018)

KIAA1199 overexpression is associated with abnormal expression of EMT markers and is a novel independent prognostic biomarker for hepatocellular carcinoma
por: Jiang, Zhengchen, et al.
Publicado: (2018)

Lysophosphatidic Acid Receptor 5 (LPAR5) Plays a Significance Role in Papillary Thyroid Cancer via Phosphatidylinositol 3-Kinase/Akt/Mammalian Target of Rapamycin (mTOR) Pathway
por: Wu, Cheng-Yong, et al.
Publicado: (2020)

Doxorubicin-Induced Cancer Cell Senescence Shows a Time Delay Effect and Is Inhibited by Epithelial-Mesenchymal Transition (EMT)
por: Hu, Xuerui, et al.
Publicado: (2019)

Microfibril-Associated Protein 2 (MFAP2) Potentiates Invasion and Migration of Melanoma by EMT and Wnt/β-Catenin Pathway
por: Chen, Zenghong, et al.
Publicado: (2020)

Murine homologue of the human KIAA1199 is implicated in hyaluronan binding and depolymerization()
por: Yoshida, Hiroyuki, et al.
Publicado: (2013)

KIAA1199 expression and hyaluronan degradation colocalize in multiple sclerosis lesions
por: Marella, Mathieu, et al.
Publicado: (2018)

KIAA1199 is induced by inflammation and enhances malignant phenotype in pancreatic cancer
por: Kohi, Shiro, et al.
Publicado: (2017)

Parthenolide Inhibits the Proliferation of MDA-T32 Papillary Thyroid Carcinoma Cells in Vitro and in Mouse Tumor Xenografts and Activates Autophagy and Apoptosis by Downregulation of the Mammalian Target of Rapamycin (mTOR)/PI3K/AKT Signaling Pathway
por: Li, Chao, et al.
Publicado: (2019)

The MEK1/2 Inhibitor AZD6244 Sensitizes BRAF-Mutant Thyroid Cancer to Vemurafenib
por: Song, Hao, et al.
Publicado: (2018)

Natural Diterpenoid Isoferritin A (IsoA) Inhibits Glioma Cell Growth and Metastasis via Regulating of TGFβ-Induced EMT Signal Pathway
por: Shen, Bin, et al.
Publicado: (2018)

Hirudin Reduces the Expression of Markers of the Extracellular Matrix in Renal Tubular Epithelial Cells in a Rat Model of Diabetic Kidney Disease Through the Hypoxia-Inducible Factor-1α (HIF-1α)/Vascular Endothelial Growth Factor (VEGF) Signaling Pathway
por: Pang, Xinxin, et al.
Publicado: (2020)

MicroRNA-145 Inhibits Cell Migration and Invasion and Regulates Epithelial-Mesenchymal Transition (EMT) by Targeting Connective Tissue Growth Factor (CTGF) in Esophageal Squamous Cell Carcinoma
por: Han, Qiang, et al.
Publicado: (2016)

Transcriptional and Epigenetic Regulation of KIAA1199 Gene Expression in Human Breast Cancer
por: Kuscu, Cem, et al.
Publicado: (2012)

KIAA1199 as a potential diagnostic biomarker of rheumatoid arthritis related to angiogenesis
por: Yang, Xinyu, et al.
Publicado: (2015)

CEMIP (KIAA1199) induces a fibrosis-like process in osteoarthritic chondrocytes
por: Deroyer, Céline, et al.
Publicado: (2019)

Overexpression of KIAA1199 is an independent prognostic marker in laryngeal squamous cell carcinoma
por: Huang, Meixiang, et al.
Publicado: (2020)

Serum KIAA1199 is an advanced-stage prognostic biomarker and metastatic oncogene in cholangiocarcinoma
por: Zhai, Xiangyu, et al.
Publicado: (2020)

CEMIP (KIAA1199) regulates inflammation, hyperplasia and fibrosis in osteoarthritis synovial membrane
por: Deroyer, Céline, et al.
Publicado: (2022)

SOX18 Affects Cell Viability, Migration, Invasiveness, and Apoptosis in Hepatocellular Carcinoma (HCC) Cells by Participating in Epithelial-to-Mesenchymal Transition (EMT) Progression and Adenosine Monophosphate Activated Protein Kinase (AMPK)/Mammalian Target of Rapamycin (mTOR)
por: Sun, Yanni, et al.
Publicado: (2019)

Ghrelin Alleviates Angiotensin II-Induced H9c2 Apoptosis: Impact of the miR-208 Family
por: Wang, Xiaotong, et al.
Publicado: (2018)

Shikonin Inhibites Migration and Invasion of Thyroid Cancer Cells by Downregulating DNMT1
por: Zhang, Yue, et al.
Publicado: (2018)

Repression of KIAA1199 attenuates Wnt-signalling and decreases the proliferation of colon cancer cells
por: Birkenkamp-Demtroder, K, et al.
Publicado: (2011)

Induction of KIAA1199/CEMIP is associated with colon cancer phenotype and poor patient survival
por: Fink, Stephen P., et al.
Publicado: (2015)

NF-κB-induced KIAA1199 promotes survival through EGFR signalling
por: Shostak, Kateryna, et al.
Publicado: (2014)

Distinct Expression Pattern of a Deafness Gene, KIAA1199, in a Primate Cochlea
por: Hosoya, Makoto, et al.
Publicado: (2016)

KIAA1199 is a secreted molecule that enhances osteoblastic stem cell migration and recruitment
por: Chen, Li, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_fhtbbacl5tjgc31iiducpi6vfj