Reverse gene-environment interaction approach to identify variants influencing body-mass index in humans

Identifying gene-environment interactions (GxEs) contributing to human cardiometabolic disorders is challenging. Here we apply a reverse GxE candidate search by deriving candidate variants from promoter-enhancer interactions that respond to dietary fatty acid challenge through altered chromatin acce...

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Detalles Bibliográficos
Autores principales: Garske, Kristina M., Pan, David Z., Miao, Zong, Bhagat, Yash V., Comenho, Caroline, Robles, Christopher R., Benhammou, Jihane N., Alvarez, Marcus, Ko, Arthur, Ye, Chun Jimmie, Pisegna, Joseph R., Mohlke, Karen L., Sinsheimer, Janet S., Laakso, Markku, Pajukanta, Päivi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6752726/
https://www.ncbi.nlm.nih.gov/pubmed/31538139
http://dx.doi.org/10.1038/s42255-019-0071-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6752726/
https://www.ncbi.nlm.nih.gov/pubmed/31538139
http://dx.doi.org/10.1038/s42255-019-0071-6

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