Cargando…

Hospital burden of pulmonary arterial hypertension in France

BACKGROUND & AIMS: Pulmonary arterial hypertension is a severe disease associated with frequent hospitalisations. This retrospective analysis of the French medical information PMSI-MSO database aimed to describe incident cases of patients with pulmonary arterial hypertension hospitalised in Fran...

Descripción completa

Detalles Bibliográficos
Autores principales: Bergot, Emmanuel, De Leotoing, Lucie, Bendjenana, Hakim, Tournier, Charlène, Vainchtock, Alexandre, Nachbaur, Gaëlle, Humbert, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6752797/
https://www.ncbi.nlm.nih.gov/pubmed/31536491
http://dx.doi.org/10.1371/journal.pone.0221211
_version_ 1783452788152336384
author Bergot, Emmanuel
De Leotoing, Lucie
Bendjenana, Hakim
Tournier, Charlène
Vainchtock, Alexandre
Nachbaur, Gaëlle
Humbert, Marc
author_facet Bergot, Emmanuel
De Leotoing, Lucie
Bendjenana, Hakim
Tournier, Charlène
Vainchtock, Alexandre
Nachbaur, Gaëlle
Humbert, Marc
author_sort Bergot, Emmanuel
collection PubMed
description BACKGROUND & AIMS: Pulmonary arterial hypertension is a severe disease associated with frequent hospitalisations. This retrospective analysis of the French medical information PMSI-MSO database aimed to describe incident cases of patients with pulmonary arterial hypertension hospitalised in France in 2013 and to document associated hospitalisation costs from the national health insurance perspective. METHODS: Cases of pulmonary arterial hypertension were identified using a diagnostic algorithm. All cases hospitalised in 2013 with no hospitalisation the previous two years were retained. All hospital stays during the year following the index hospitalisation were extracted, and classified as incident stays, monitoring stays or stays due to disease worsening. Costs were attributed from French national tariffs. RESULTS: 384 patients in France were hospitalised with incident pulmonary arterial hypertension in 2013. Over the following twelve months, patients made 1,271 stays related to pulmonary arterial hypertension (415 incident stays, 604 monitoring stays and 252 worsening stays). Mean age was 59.6 years and 241 (62.8%) patients were women. Liver disease and connective tissue diseases were documented in 62 patients (16.1%) each. Thirty-one patients (8.1%) died during hospitalisation and four (1.0%) received a lung/heart-lung transplantation. The total annual cost of these hospitalisations was € 3,640,382. € 2,985,936 was attributable to standard tariffs (82.0%), € 463,325 to additional ICU stays (12.7%) and € 191,118 to expensive drugs (5.2%). The mean cost/stay was € 2,864, ranging from € 1,282 for monitoring stays to € 7,285 for worsening stays. CONCLUSIONS: Although pulmonary arterial hypertension is rare, it carries a high economic burden.
format Online
Article
Text
id pubmed-6752797
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Public Library of Science
record_format MEDLINE/PubMed
spelling pubmed-67527972019-09-27 Hospital burden of pulmonary arterial hypertension in France Bergot, Emmanuel De Leotoing, Lucie Bendjenana, Hakim Tournier, Charlène Vainchtock, Alexandre Nachbaur, Gaëlle Humbert, Marc PLoS One Research Article BACKGROUND & AIMS: Pulmonary arterial hypertension is a severe disease associated with frequent hospitalisations. This retrospective analysis of the French medical information PMSI-MSO database aimed to describe incident cases of patients with pulmonary arterial hypertension hospitalised in France in 2013 and to document associated hospitalisation costs from the national health insurance perspective. METHODS: Cases of pulmonary arterial hypertension were identified using a diagnostic algorithm. All cases hospitalised in 2013 with no hospitalisation the previous two years were retained. All hospital stays during the year following the index hospitalisation were extracted, and classified as incident stays, monitoring stays or stays due to disease worsening. Costs were attributed from French national tariffs. RESULTS: 384 patients in France were hospitalised with incident pulmonary arterial hypertension in 2013. Over the following twelve months, patients made 1,271 stays related to pulmonary arterial hypertension (415 incident stays, 604 monitoring stays and 252 worsening stays). Mean age was 59.6 years and 241 (62.8%) patients were women. Liver disease and connective tissue diseases were documented in 62 patients (16.1%) each. Thirty-one patients (8.1%) died during hospitalisation and four (1.0%) received a lung/heart-lung transplantation. The total annual cost of these hospitalisations was € 3,640,382. € 2,985,936 was attributable to standard tariffs (82.0%), € 463,325 to additional ICU stays (12.7%) and € 191,118 to expensive drugs (5.2%). The mean cost/stay was € 2,864, ranging from € 1,282 for monitoring stays to € 7,285 for worsening stays. CONCLUSIONS: Although pulmonary arterial hypertension is rare, it carries a high economic burden. Public Library of Science 2019-09-19 /pmc/articles/PMC6752797/ /pubmed/31536491 http://dx.doi.org/10.1371/journal.pone.0221211 Text en © 2019 Bergot et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Bergot, Emmanuel
De Leotoing, Lucie
Bendjenana, Hakim
Tournier, Charlène
Vainchtock, Alexandre
Nachbaur, Gaëlle
Humbert, Marc
Hospital burden of pulmonary arterial hypertension in France
title Hospital burden of pulmonary arterial hypertension in France
title_full Hospital burden of pulmonary arterial hypertension in France
title_fullStr Hospital burden of pulmonary arterial hypertension in France
title_full_unstemmed Hospital burden of pulmonary arterial hypertension in France
title_short Hospital burden of pulmonary arterial hypertension in France
title_sort hospital burden of pulmonary arterial hypertension in france
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6752797/
https://www.ncbi.nlm.nih.gov/pubmed/31536491
http://dx.doi.org/10.1371/journal.pone.0221211
work_keys_str_mv AT bergotemmanuel hospitalburdenofpulmonaryarterialhypertensioninfrance
AT deleotoinglucie hospitalburdenofpulmonaryarterialhypertensioninfrance
AT bendjenanahakim hospitalburdenofpulmonaryarterialhypertensioninfrance
AT tourniercharlene hospitalburdenofpulmonaryarterialhypertensioninfrance
AT vainchtockalexandre hospitalburdenofpulmonaryarterialhypertensioninfrance
AT nachbaurgaelle hospitalburdenofpulmonaryarterialhypertensioninfrance
AT humbertmarc hospitalburdenofpulmonaryarterialhypertensioninfrance