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Identification and characterization of a novel heparan sulfate-binding domain in Activin A longest variants and implications for function
Activins regulate numerous processes including inflammation and are synthesized as precursors consisting of a long N-terminal pro-region and a mature protein. Genomic human databases currently list three activin A (Act A) variants termed X1, X2 and X3. The X3 variant is the shortest, lacks N-termina...
Autores principales: | Yang, Evan, Mundy, Christina, Rappaport, Eric F., Pacifici, Maurizio, Billings, Paul C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6752817/ https://www.ncbi.nlm.nih.gov/pubmed/31536599 http://dx.doi.org/10.1371/journal.pone.0222784 |
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