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Wikipedia network analysis of cancer interactions and world influence
We apply the Google matrix algorithms for analysis of interactions and influence of 37 cancer types, 203 cancer drugs and 195 world countries using the network of 5 416 537 English Wikipedia articles with all their directed hyperlinks. The PageRank algorithm provides a ranking of cancers which has 6...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6752824/ https://www.ncbi.nlm.nih.gov/pubmed/31536541 http://dx.doi.org/10.1371/journal.pone.0222508 |
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author | Rollin, Guillaume Lages, José Shepelyansky, Dima L. |
author_facet | Rollin, Guillaume Lages, José Shepelyansky, Dima L. |
author_sort | Rollin, Guillaume |
collection | PubMed |
description | We apply the Google matrix algorithms for analysis of interactions and influence of 37 cancer types, 203 cancer drugs and 195 world countries using the network of 5 416 537 English Wikipedia articles with all their directed hyperlinks. The PageRank algorithm provides a ranking of cancers which has 60% and 70% overlaps with the top 10 deadliest cancers extracted from World Health Organization GLOBOCAN 2018 and Global Burden of Diseases Study 2017, respectively. The recently developed reduced Google matrix algorithm gives networks of interactions between cancers, drugs and countries taking into account all direct and indirect links between these selected 435 entities. These reduced networks allow to obtain sensitivity of countries to specific cancers and drugs. The strongest links between cancers and drugs are in good agreement with the approved medical prescriptions of specific drugs to specific cancers. We argue that this analysis of knowledge accumulated in Wikipedia provides useful complementary global information about interdependencies between cancers, drugs and world countries. |
format | Online Article Text |
id | pubmed-6752824 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-67528242019-09-27 Wikipedia network analysis of cancer interactions and world influence Rollin, Guillaume Lages, José Shepelyansky, Dima L. PLoS One Research Article We apply the Google matrix algorithms for analysis of interactions and influence of 37 cancer types, 203 cancer drugs and 195 world countries using the network of 5 416 537 English Wikipedia articles with all their directed hyperlinks. The PageRank algorithm provides a ranking of cancers which has 60% and 70% overlaps with the top 10 deadliest cancers extracted from World Health Organization GLOBOCAN 2018 and Global Burden of Diseases Study 2017, respectively. The recently developed reduced Google matrix algorithm gives networks of interactions between cancers, drugs and countries taking into account all direct and indirect links between these selected 435 entities. These reduced networks allow to obtain sensitivity of countries to specific cancers and drugs. The strongest links between cancers and drugs are in good agreement with the approved medical prescriptions of specific drugs to specific cancers. We argue that this analysis of knowledge accumulated in Wikipedia provides useful complementary global information about interdependencies between cancers, drugs and world countries. Public Library of Science 2019-09-19 /pmc/articles/PMC6752824/ /pubmed/31536541 http://dx.doi.org/10.1371/journal.pone.0222508 Text en © 2019 Rollin et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Rollin, Guillaume Lages, José Shepelyansky, Dima L. Wikipedia network analysis of cancer interactions and world influence |
title | Wikipedia network analysis of cancer interactions and world influence |
title_full | Wikipedia network analysis of cancer interactions and world influence |
title_fullStr | Wikipedia network analysis of cancer interactions and world influence |
title_full_unstemmed | Wikipedia network analysis of cancer interactions and world influence |
title_short | Wikipedia network analysis of cancer interactions and world influence |
title_sort | wikipedia network analysis of cancer interactions and world influence |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6752824/ https://www.ncbi.nlm.nih.gov/pubmed/31536541 http://dx.doi.org/10.1371/journal.pone.0222508 |
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