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Xist RNA in action: Past, present, and future
In mammals, dosage compensation of sex chromosomal genes between females (XX) and males (XY) is achieved through X-chromosome inactivation (XCI). The X-linked X-inactive-specific transcript (Xist) long noncoding RNA is indispensable for XCI and initiates the process early during development by sprea...
Autores principales: | Loda, Agnese, Heard, Edith |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6752956/ https://www.ncbi.nlm.nih.gov/pubmed/31537017 http://dx.doi.org/10.1371/journal.pgen.1008333 |
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