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Photopharmacologic Vision Restoration Reduces Pathological Rhythmic Field Potentials in Blind Mouse Retina

Photopharmacology has yielded compounds that have potential to restore impaired visual responses resulting from outer retinal degeneration diseases such as retinitis pigmentosa. Here we evaluate two photoswitchable azobenzene ion channel blockers, DAQ and DAA for vision restoration. DAQ exerts its e...

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Detalles Bibliográficos
Autores principales: Hüll, Katharina, Benster, Tyler, Manookin, Michael B., Trauner, Dirk, Van Gelder, Russell N., Laprell, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753071/
https://www.ncbi.nlm.nih.gov/pubmed/31537864
http://dx.doi.org/10.1038/s41598-019-49999-w