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Photopharmacologic Vision Restoration Reduces Pathological Rhythmic Field Potentials in Blind Mouse Retina
Photopharmacology has yielded compounds that have potential to restore impaired visual responses resulting from outer retinal degeneration diseases such as retinitis pigmentosa. Here we evaluate two photoswitchable azobenzene ion channel blockers, DAQ and DAA for vision restoration. DAQ exerts its e...
Autores principales: | Hüll, Katharina, Benster, Tyler, Manookin, Michael B., Trauner, Dirk, Van Gelder, Russell N., Laprell, Laura |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753071/ https://www.ncbi.nlm.nih.gov/pubmed/31537864 http://dx.doi.org/10.1038/s41598-019-49999-w |
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