Cargando…

Statin use and the risk of colorectal cancer in a population-based electronic health records study

There is extensive debate regarding the protective effect of 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors (statins) on colorectal cancer (CRC). We aimed to assess the association between CRC risk and exposure to statins using a large cohort with prescription data. We carried out a case...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ibáñez-Sanz, Gemma, Guinó, Elisabet, Pontes, Caridad, Quijada-Manuitt, Mª Ángeles, de la Peña-Negro, Luisa C, Aragón, María, Domínguez, Marga, Rodríguez-Alonso, Lorena, Blasco, Alex, García-Rodríguez, Ana, Morros, Rosa, Moreno, Victor
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753123/ https://www.ncbi.nlm.nih.gov/pubmed/31537841 http://dx.doi.org/10.1038/s41598-019-49877-5

Ejemplares similares

The use and adherence of oral anticoagulants in Primary Health Care in Catalunya, Spain: A real-world data cohort study
por: Giner-Soriano, Maria, et al.
Publicado: (2020)

Polygenic risk score across distinct colorectal cancer screening outcomes: from premalignant polyps to colorectal cancer
por: Obón-Santacana, Mireia, et al.
Publicado: (2021)

Gut microbiome diversity detected by high-coverage 16S and shotgun sequencing of paired stool and colon sample
por: Mas-Lloret, Joan, et al.
Publicado: (2020)

Meta-Analysis and Validation of a Colorectal Cancer Risk Prediction Model Using Deep Sequenced Fecal Metagenomes
por: Obón-Santacana, Mireia, et al.
Publicado: (2022)

Proton pump inhibitors reduce the accuracy of faecal immunochemical test for detecting advanced colorectal neoplasia in symptomatic patients
por: Rodriguez-Alonso, Lorena, et al.
Publicado: (2018)

Identifying Reasons for Statin Nonuse in Patients With Diabetes Using Deep Learning of Electronic Health Records
por: Sarraju, Ashish, et al.
Publicado: (2023)

Variability in prescription drug expenditures explained by adjusted clinical groups (ACG) case-mix: A cross-sectional study of patient electronic records in primary care
por: Aguado, Alba, et al.
Publicado: (2008)

Statins and Risk of Diabetes: An analysis of electronic medical records to evaluate possible bias due to differential survival
por: Danaei, Goodarz, et al.
Publicado: (2013)

Impact of pre-admission antithrombotic therapy on disease severity and mortality in patients hospitalized for COVID-19
por: Corrochano, Mariana, et al.
Publicado: (2021)

Discovery and Validation of New Potential Biomarkers for Early Detection of Colon Cancer
por: Solé, Xavier, et al.
Publicado: (2014)

Identifying causal models between genetically regulated methylation patterns and gene expression in healthy colon tissue
por: Díez-Villanueva, Anna, et al.
Publicado: (2021)

Impact of the COVID-19 Pandemic on the Incidence of Suicidal Behaviors: A Retrospective Analysis of Integrated Electronic Health Records in a Population of 7.5 Million
por: Valero-Bover, Damià, et al.
Publicado: (2022)

Statin use is associated with reduced mortality after respiratory viral infection
por: Franco-Peláez, Juan Antonio, et al.
Publicado: (2021)

Risk Model for Colorectal Cancer in Spanish Population Using Environmental and Genetic Factors: Results from the MCC-Spain study
por: Ibáñez-Sanz, Gemma, et al.
Publicado: (2017)

Corrigendum: Risk Model for Colorectal Cancer in Spanish Population Using Environmental and Genetic Factors: Results from the MCC-Spain study
por: Ibáñez-Sanz, Gemma, et al.
Publicado: (2017)

Effectiveness of an intervention designed to optimize statins use: a primary prevention randomized clinical trial
por: Fàbregas, Mireia, et al.
Publicado: (2014)

Diagnosis and Management of Statin Intolerance
por: Alonso, Rodrigo, et al.
Publicado: (2019)

Statins in Non-alcoholic Steatohepatitis
por: Torres-Peña, Jose D., et al.
Publicado: (2021)

A microRNA Signature for the Diagnosis of Statins Intolerance
por: Mangas, Alipio, et al.
Publicado: (2022)

Comprehensive analysis of copy number aberrations in microsatellite stable colon cancer in view of stromal component
por: Alonso, M Henar, et al.
Publicado: (2017)

Statins as Modulators of Regulatory T-Cell Biology
por: Forero-Peña, David A., et al.
Publicado: (2013)

Description of the use of multicriteria to support pricing and reimbursement decisions by European health technology assessment bodies
por: Elvira, David, et al.
Publicado: (2021)

The challenges of access to innovative medicines with limited evidence in the European Union
por: Vallano, Antonio, et al.
Publicado: (2023)

Common Statin Intolerance Variants in ABCB1 and LILRB5 Show Synergistic Effects on Statin Response: An Observational Study Using Electronic Health Records
por: Melhem, Alaa’ Lutfi, et al.
Publicado: (2021)

Statin Therapy and the Assessment of Hepatoprotection in Patients with Dyslipidaemia
por: Beznă, Marinela, et al.
Publicado: (2023)

Formulation and Evaluation of Loperamide HCl Oro Dispersible Tablets
por: Alejandro, Blasco, et al.
Publicado: (2020)

Polymorphisms in prostaglandin synthase 2/cyclooxygenase 2 (PTGS2/COX2) and risk of colorectal cancer
por: Cox, D G, et al.
Publicado: (2004)

Modest effect of statins on fasting glucose in a longitudinal electronic health record based cohort
por: Haldar, Tanushree, et al.
Publicado: (2022)

Evidence supporting regulatory-decision making on orphan medicinal products authorisation in Europe: methodological uncertainties
por: Pontes, Caridad, et al.
Publicado: (2018)

Noninvasive Mechanical Ventilation in Patients with Severe Pneumonia
por: Blasco-Navalpotro, Miguel Angel, et al.
Publicado: (2013)

Statin Intolerance and Suboptimal Statin Therapy
por: Tada, Hayato, et al.
Publicado: (2019)

Undertreatment or Overtreatment With Statins: Where Are We?
por: García-Fernández-Bravo, Irene, et al.
Publicado: (2022)

Future Prospects of Colorectal Cancer Screening: Characterizing Interval Cancers
por: Ibáñez-Sanz, Gemma, et al.
Publicado: (2021)

A Systematic Review and Meta-Analysis of Validation Studies Performed on Dietary Record Apps
por: Zhang, Liangzi, et al.
Publicado: (2021)

Aberrant gene expression in mucosa adjacent to tumor reveals a molecular crosstalk in colon cancer
por: Sanz-Pamplona, Rebeca, et al.
Publicado: (2014)

Non-selective β-blockers in advanced cirrhosis: a critical review of the effects on overall survival and renal function
por: Blasco-Algora, Sara, et al.
Publicado: (2016)

Statins Inhibit HIV-1 Infection by Down-regulating Rho Activity
por: del Real, Gustavo, et al.
Publicado: (2004)

Acciones de enfermería en pacientes con Síndrome de Inmunodeficiencia Adquirida (SIDA)
por: Rodríguez Escalona, Linda Caridad
Publicado: (2001)

A Nitric Oxide-Donating Statin Decreases Portal Pressure with a Better Toxicity Profile than Conventional Statins in Cirrhotic Rats
por: Rodríguez, Sarai, et al.
Publicado: (2017)

Automatic Estimation of the Most Likely Drug Combination in Electronic Health Records Using the Smooth Algorithm: Development and Validation Study
por: Ouchi, Dan, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_88jnr4btk33n2241a2lcbabn2m