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Probing the dynamic stalk region of the ribosome using solution NMR

We describe an NMR approach based on the measurement of residual dipolar couplings (RDCs) to probe the structural and motional properties of the dynamic regions of the ribosome. Alignment of intact 70S ribosomes in filamentous bacteriophage enabled measurement of RDCs in the mobile C-terminal domain...

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Detalles Bibliográficos
Autores principales:	Wang, Xiaolin, Kirkpatrick, John P., Launay, Hélène M. M., de Simone, Alfonso, Häussinger, Daniel, Dobson, Christopher M., Vendruscolo, Michele, Cabrita, Lisa D., Waudby, Christopher A., Christodoulou, John
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753160/ https://www.ncbi.nlm.nih.gov/pubmed/31537834 http://dx.doi.org/10.1038/s41598-019-49190-1

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