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Development of Patient-Derived Preclinical Platform for Metastatic Pancreatic Cancer: PDOX and a Subsequent Organoid Model System Using Percutaneous Biopsy Samples

Pancreatic ductal adenocarcinoma (PDAC) is the most lethal malignant tumor and more than 50% patients are diagnosed at metastatic stage. The preclinical model systems that reflect the genetic heterogeneity of metastatic tumors are urgently needed to guide optimal treatment. This study describes the...

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Detalles Bibliográficos
Autores principales:	Choi, Sun Il, Jeon, A-Ra, Kim, Min Kyeong, Lee, Yu-Sun, Im, Ji Eun, Koh, Jung-Wook, Han, Sung-Sik, Kong, Sun-Young, Yoon, Kyong-Ah, Koh, Young-Hwan, Lee, Ju Hee, Lee, Woo Jin, Park, Sang-Jae, Hong, En Kyung, Woo, Sang Myung, Kim, Yun-Hee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753223/ https://www.ncbi.nlm.nih.gov/pubmed/31572675 http://dx.doi.org/10.3389/fonc.2019.00875

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