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Bacterial RNA Contributes to the Down-Modulation of MHC-II Expression on Monocytes/Macrophages Diminishing CD4(+) T Cell Responses

Brucella abortus, the causative agent of brucellosis, displays many resources to evade T cell responses conducive to persist inside the host. Our laboratory has previously showed that infection of human monocytes with B. abortus down-modulates the IFN-γ-induced MHC-II expression. Brucella outer memb...

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Detalles Bibliográficos
Autores principales: Milillo, M. Ayelén, Trotta, Aldana, Serafino, Agustina, Marin Franco, José Luis, Marinho, Fábio V., Alcain, Julieta, Genoula, Melanie, Balboa, Luciana, Oliveira, Sergio Costa, Giambartolomei, Guillermo H., Barrionuevo, Paula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753364/
https://www.ncbi.nlm.nih.gov/pubmed/31572389
http://dx.doi.org/10.3389/fimmu.2019.02181