CTCF cooperates with CtIP to drive homologous recombination repair of double-strand breaks

The pleiotropic CCCTC-binding factor (CTCF) plays a role in homologous recombination (HR) repair of DNA double-strand breaks (DSBs). However, the precise mechanistic role of CTCF in HR remains largely unclear. Here, we show that CTCF engages in DNA end resection, which is the initial, crucial step i...

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Detalles Bibliográficos
Autores principales: Hwang, Soon Young, Kang, Mi Ae, Baik, Chul Joon, Lee, Yejin, Hang, Ngo Thanh, Kim, Byung-Gyu, Han, Joo Seok, Jeong, Jae-Hoon, Park, Daechan, Myung, Kyungjae, Lee, Jong-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753481/
https://www.ncbi.nlm.nih.gov/pubmed/31340001
http://dx.doi.org/10.1093/nar/gkz639

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753481/
https://www.ncbi.nlm.nih.gov/pubmed/31340001
http://dx.doi.org/10.1093/nar/gkz639

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