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Bioprocess Development for Lantibiotic Ruminococcin-A Production in Escherichia coli and Kinetic Insights Into LanM Enzymes Catalysis

Ruminococcin-A (RumA) is a peptide antibiotic with post-translational modifications including thioether cross-links formed from non-canonical amino acids, called lanthionines, synthesized by a dedicated lanthionine-generating enzyme RumM. RumA is naturally produced by Ruminococcus gnavus, which is p...

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Detalles Bibliográficos
Autores principales:	Ongey, Elvis L., Santolin, Lara, Waldburger, Saskia, Adrian, Lorenz, Riedel, Sebastian L., Neubauer, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753504/ https://www.ncbi.nlm.nih.gov/pubmed/31572338 http://dx.doi.org/10.3389/fmicb.2019.02133

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