A case of simultaneous acute cardio-cerebral infarction in a woman with essential thrombocythemia

Essential thrombocythemia (ET) can cause arterial embolism. Patients with arterial thrombosis usually have additional risk factors, such as smoking and hypertension. We report a 70-year-old woman with ET who had no risk factors, except for age. Cranial magnetic resonance imaging showed fresh lacunar...

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Autores principales: Wang, LingQing, Mao, Xiang, Zheng, JiPing, Gu, XingJian, Yang, JianGuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753560/
https://www.ncbi.nlm.nih.gov/pubmed/31426696
http://dx.doi.org/10.1177/0300060519865062
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author Wang, LingQing
Mao, Xiang
Zheng, JiPing
Gu, XingJian
Yang, JianGuang
author_facet Wang, LingQing
Mao, Xiang
Zheng, JiPing
Gu, XingJian
Yang, JianGuang
author_sort Wang, LingQing
collection PubMed
description Essential thrombocythemia (ET) can cause arterial embolism. Patients with arterial thrombosis usually have additional risk factors, such as smoking and hypertension. We report a 70-year-old woman with ET who had no risk factors, except for age. Cranial magnetic resonance imaging showed fresh lacunar infarction in several lobes. Electrocardiography showed ST-segment elevation in leads II, III, and aVF. Coronary angioplasty and stenting were successfully performed. We checked the bone marrow and performed genetic testing. The Janus kinase 2 (JAK2) V617F gene mutation was found. This case was a rare initial presentation of previously undiagnosed ET with embolism of cardiovascular and cerebral vessels. Anti-platelet drugs and hydroxyurea were used to prevent further thrombosis in the coronary and cerebral arteries.
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spelling pubmed-67535602019-09-25 A case of simultaneous acute cardio-cerebral infarction in a woman with essential thrombocythemia Wang, LingQing Mao, Xiang Zheng, JiPing Gu, XingJian Yang, JianGuang J Int Med Res Case Reports Essential thrombocythemia (ET) can cause arterial embolism. Patients with arterial thrombosis usually have additional risk factors, such as smoking and hypertension. We report a 70-year-old woman with ET who had no risk factors, except for age. Cranial magnetic resonance imaging showed fresh lacunar infarction in several lobes. Electrocardiography showed ST-segment elevation in leads II, III, and aVF. Coronary angioplasty and stenting were successfully performed. We checked the bone marrow and performed genetic testing. The Janus kinase 2 (JAK2) V617F gene mutation was found. This case was a rare initial presentation of previously undiagnosed ET with embolism of cardiovascular and cerebral vessels. Anti-platelet drugs and hydroxyurea were used to prevent further thrombosis in the coronary and cerebral arteries. SAGE Publications 2019-08-20 2019-09 /pmc/articles/PMC6753560/ /pubmed/31426696 http://dx.doi.org/10.1177/0300060519865062 Text en © The Author(s) 2019 http://creativecommons.org/licenses/by-nc/4.0/ Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Reports
Wang, LingQing
Mao, Xiang
Zheng, JiPing
Gu, XingJian
Yang, JianGuang
A case of simultaneous acute cardio-cerebral infarction in a woman with essential thrombocythemia
title A case of simultaneous acute cardio-cerebral infarction in a woman with essential thrombocythemia
title_full A case of simultaneous acute cardio-cerebral infarction in a woman with essential thrombocythemia
title_fullStr A case of simultaneous acute cardio-cerebral infarction in a woman with essential thrombocythemia
title_full_unstemmed A case of simultaneous acute cardio-cerebral infarction in a woman with essential thrombocythemia
title_short A case of simultaneous acute cardio-cerebral infarction in a woman with essential thrombocythemia
title_sort case of simultaneous acute cardio-cerebral infarction in a woman with essential thrombocythemia
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753560/
https://www.ncbi.nlm.nih.gov/pubmed/31426696
http://dx.doi.org/10.1177/0300060519865062
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